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Cancer Immunology Research|June 16, 2025
In Vivo Labeling Resolves Distinct Temporal, Spatial, and Functional Properties of Tumor Macrophages and Identifies Subset-Specific Effects of PD-L1 BlockadeColin Y C Lee, Isaac Dean, Nathan Richoz, et al.Mabs|January 5, 2021
Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancerDarren J Schofield, Jennifer Percival-Alwyn, Mateusz Rytelewski, et al.Cancer Biology & Therapy|January 11, 2024
Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor modelsBrajesh P Kaistha, Gozde Kar, Andreas Dannhorn, et al.Molecular Therapy. Oncology|April 10, 2024
Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12Cheyne Kurokawa, Sonia Agrawal, Abhisek Mitra, et al.Molecular Cancer Therapeutics|March 17, 2018
Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion ProteinMichael D Oberst, Catherine Augé, Chad Morris, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 11, 2017
A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 AgonistRebecca Leyland, Amanda Watkins, Kathy A Mulgrew, et al.Science Translational Medicine|April 15, 2016
The Human Vaccines Project: A roadmap for cancer vaccine developmentPedro Romero, Jacques Banchereau, Nina Bhardwaj, et al.Nature Communications|January 24, 2024
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunityIsaac Dean, Colin Y C Lee, Zewen K Tuong, et al.Journal for Immunotherapy of Cancer|August 4, 2025
An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine releaseMiguel Gaspar, Marina Natoli, Laure Castan, et al.Nature Immunology|July 31, 2019
PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1<sup>+</sup>CD38<sup>hi</sup> cells and anti-PD-1 resistanceVivek Verma, Rajeev K Shrimali, Shamim Ahmad, et al.Pageof 5