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Molecular Cancer Therapeutics|June 6, 2018
Glucuronide-Linked Antibody-Tubulysin Conjugates Display Activity in MDR+ and Heterogeneous Tumor ModelsPatrick J Burke, Joseph Z Hamilton, Thomas A Pires, et al.
Journal of Medicinal Chemistry|March 4, 2005
Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugatesScott C Jeffrey, Michael Y Torgov, Jamie B Andreyka, et al.
Bioconjugate Chemistry|May 18, 2006
Development and properties of beta-glucuronide linkers for monoclonal antibody-drug conjugatesScott C Jeffrey, Jamie B Andreyka, Starr X Bernhardt, et al.
Chemmedchem|December 28, 2020
Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific ConjugationJoseph Z Hamilton, Thomas A Pires, Jamie A Mitchell, et al.
Molecular Cancer Therapeutics|January 8, 2017
Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug ConjugatesPatrick J Burke, Joseph Z Hamilton, Scott C Jeffrey, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 16, 2013
Development of orally active inhibitors of protein and cellular fucosylationNicole M Okeley, Stephen C Alley, Martha E Anderson, et al.
Molecular Cancer Therapeutics|March 6, 2016
Development of Novel Quaternary Ammonium Linkers for Antibody-Drug ConjugatesPatrick J Burke, Joseph Z Hamilton, Thomas A Pires, et al.
Blood|June 18, 2013
SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AMLMay S Kung Sutherland, Roland B Walter, Scott C Jeffrey, et al.
Molecular Cancer Therapeutics|December 4, 2020
Development of Novel Antibody-Camptothecin ConjugatesRyan D Lyski, Lauren B Bou, Uland Y Lau, et al.
Bioconjugate Chemistry|July 2, 2013
A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technologyScott C Jeffrey, Patrick J Burke, Robert P Lyon, et al.
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