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Journal of Medicinal Chemistry
|
October 8, 2024
Discovery of the First Clinical Protein Degrader for the Treatment of Autoimmune Indications: Orally Bioavailable and Selective IRAK4 Degrader KT-474
Scott D Edmondson
Angewandte Chemie (International Ed. in English)
|
May 2, 2018
The Total Synthesis of Spirotryprostatin A
Scott D Edmondson, Samuel J Danishefsky
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2019
Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges
Scott D Edmondson, Bin Yang, Charlene Fallan
The Journal of Organic Chemistry
|
October 25, 2001
Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 2. Functionalization of Advanced Polycyclic Precursors to the 9-Epi and 8,9-Dehydro Congeners
Leo A. Paquette, Scott D. Edmondson, Nathaniel Monck, et al.
The Journal of Organic Chemistry
|
October 25, 2001
Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 1. A Solution to the Problem of Chirality Merger during Elaboration of the Entire Carbotricyclic Framework
Leo A. Paquette, Shogo Nakatani, Thomas M. Zydowsky, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
December 20, 2003
Crystallization and preliminary X-ray diffraction analysis of the catalytic domain of recombinant human phosphodiesterase 3B
Sangita B Patel, Jeffrey P Varnerin, Michael R Tota, et al.
Journal of Medicinal Chemistry
|
August 18, 2020
Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase
Sébastien L Degorce, Omid Tavana, Erica Banks, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 16, 2011
Discovery of pyrimidine carboxamides as potent and selective CCK1 receptor agonists
Liping Wang, James A Hubert, Susan J Lee, et al.
Biochemistry
|
May 19, 2004
Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity
Giovanna Scapin, Sangita B Patel, Christine Chung, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 15, 2007
Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors
Jason M Cox, Bart Harper, Anthony Mastracchio, et al.
Page
of 5
Search research articles
Search
Showing results (1-10 of 44) with videos related to
Sort By:
Page
of 5
Journal of Medicinal Chemistry
|
October 8, 2024
Discovery of the First Clinical Protein Degrader for the Treatment of Autoimmune Indications: Orally Bioavailable and Selective IRAK4 Degrader KT-474
Scott D Edmondson
Angewandte Chemie (International Ed. in English)
|
May 2, 2018
The Total Synthesis of Spirotryprostatin A
Scott D Edmondson, Samuel J Danishefsky
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2019
Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges
Scott D Edmondson, Bin Yang, Charlene Fallan
The Journal of Organic Chemistry
|
October 25, 2001
Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 2. Functionalization of Advanced Polycyclic Precursors to the 9-Epi and 8,9-Dehydro Congeners
Leo A. Paquette, Scott D. Edmondson, Nathaniel Monck, et al.
The Journal of Organic Chemistry
|
October 25, 2001
Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 1. A Solution to the Problem of Chirality Merger during Elaboration of the Entire Carbotricyclic Framework
Leo A. Paquette, Shogo Nakatani, Thomas M. Zydowsky, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
December 20, 2003
Crystallization and preliminary X-ray diffraction analysis of the catalytic domain of recombinant human phosphodiesterase 3B
Sangita B Patel, Jeffrey P Varnerin, Michael R Tota, et al.
Journal of Medicinal Chemistry
|
August 18, 2020
Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase
Sébastien L Degorce, Omid Tavana, Erica Banks, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 16, 2011
Discovery of pyrimidine carboxamides as potent and selective CCK1 receptor agonists
Liping Wang, James A Hubert, Susan J Lee, et al.
Biochemistry
|
May 19, 2004
Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity
Giovanna Scapin, Sangita B Patel, Christine Chung, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 15, 2007
Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors
Jason M Cox, Bart Harper, Anthony Mastracchio, et al.
Page
of 5