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Bioorganic & Medicinal Chemistry Letters
|
July 28, 2020
Optimization of a series of potent, selective and orally bioavailable SYK inhibitors
Neil P Grimster, Lakshmaiah Gingipalli, Bernard Barlaam, et al.
Journal of Medicinal Chemistry
|
September 27, 2021
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
Jeffrey W Johannes, Amber Balazs, Derek Barratt, et al.
Journal of Medicinal Chemistry
|
December 10, 2024
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
Jeffrey W Johannes, Amber Y S Balazs, Derek Barratt, et al.
Journal of Medicinal Chemistry
|
September 3, 2025
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki, et al.
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Showing results (41-50 of 44) with videos related to
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This site can display upto 44 results.
Bioorganic & Medicinal Chemistry Letters
|
July 28, 2020
Optimization of a series of potent, selective and orally bioavailable SYK inhibitors
Neil P Grimster, Lakshmaiah Gingipalli, Bernard Barlaam, et al.
Journal of Medicinal Chemistry
|
September 27, 2021
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
Jeffrey W Johannes, Amber Balazs, Derek Barratt, et al.
Journal of Medicinal Chemistry
|
December 10, 2024
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
Jeffrey W Johannes, Amber Y S Balazs, Derek Barratt, et al.
Journal of Medicinal Chemistry
|
September 3, 2025
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki, et al.
Page
of 5