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Bioanalysis|March 14, 2023
The GSK Bioanalytical Hub model in bioanalysis: maximizing the synergies of co-locating various platforms in support of regulated and nonregulated study end pointsScott G Summerfield, Huaping Tang, Vilma Decman, et al.Bioanalysis|June 25, 2014
Integrating internal and external bioanalytical support to deliver a diversified pharmaceutical portfolioScott G Summerfield, Christopher Evans, Neil Spooner, et al.The Journal of Pharmacology and Experimental Therapeutics|April 5, 2007
Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fractionScott G Summerfield, Kevin Read, David J Begley, et al.British Journal of Pharmacology|June 14, 2006
Investigation into the role of P2X(3)/P2X(2/3) receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological studyCaroline J Sharp, Alison J Reeve, Sue D Collins, et al.The Journal of Pharmacology and Experimental Therapeutics|December 7, 2005
Improving the in vitro prediction of in vivo central nervous system penetration: integrating permeability, P-glycoprotein efflux, and free fractions in blood and brainScott G Summerfield, Alexander J Stevens, Leanne Cutler, et al.Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|January 26, 2012
Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugsRoger N Gunn, Scott G Summerfield, Cristian A Salinas, et al.The Journal of Pharmacology and Experimental Therapeutics|March 8, 2018
Drug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, et al.The Journal of Pharmacology and Experimental Therapeutics|December 2, 2004
The cyclooxygenase-2 inhibitor GW406381X [2-(4-ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] is effective in animal models of neuropathic pain and central sensitizationSharon Bingham, Paul J Beswick, Chas Bountra, et al.Bioconjugate Chemistry|February 1, 2021
<i>In Vivo</i> Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin BindersJulien C Vantourout, Andrew M Mason, Josephine Yuen, et al.Pageof 2