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Molecular Pharmaceutics
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July 25, 2018
Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates
Zhonghua Pei, Chunjiao Chen, Jinhua Chen, et al.
American Journal of Hematology
|
January 3, 2023
Targeting MCL-1 and BCL-2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non-Hodgkin lymphoma: Results from preclinical models and a Phase Ib study
Elisabeth A Lasater, Dhara N Amin, Rajat Bannerji, et al.
Science (New York, N.Y.)
|
January 29, 2026
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Junedh M Amrute, In-Hyuk Jung, Tracy Yamawaki, et al.
Journal of Medicinal Chemistry
|
September 27, 2021
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
Jeffrey W Johannes, Amber Balazs, Derek Barratt, et al.
Journal of Medicinal Chemistry
|
January 27, 2025
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations
William McCoull, Clare Thomson, Erin Braybrooke, et al.
Nature Cancer
|
June 5, 2023
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
Thijs J Hagenbeek, Jason R Zbieg, Marc Hafner, et al.
Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|
April 27, 2019
Improved Outcomes Associated with the use of Shock Protocols: Updates from the National Cardiogenic Shock Initiative
Mir B Basir, Navin K Kapur, Kirit Patel, et al.
Journal of Medicinal Chemistry
|
January 9, 2014
Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymerase
Robert G Gentles, Min Ding, John A Bender, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
October 27, 2025
PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with PIK3CA-Mutated Solid Tumors and in Preclinical Models
Dejan Juric, Kyung Song, Radia M Johnson, et al.
Nature Communications
|
June 27, 2026
Covalent pan-TEAD inhibitors block YAP activity and demonstrate brain penetrance in a Hippo-dependent cancer model
Thijs J Hagenbeek, Jason Zbieg, Russell Smith, et al.
Page
of 25
Search research articles
Search
Showing results (231-240 of 241) with videos related to
Sort By:
Page
of 25
Molecular Pharmaceutics
|
July 25, 2018
Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates
Zhonghua Pei, Chunjiao Chen, Jinhua Chen, et al.
American Journal of Hematology
|
January 3, 2023
Targeting MCL-1 and BCL-2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non-Hodgkin lymphoma: Results from preclinical models and a Phase Ib study
Elisabeth A Lasater, Dhara N Amin, Rajat Bannerji, et al.
Science (New York, N.Y.)
|
January 29, 2026
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Junedh M Amrute, In-Hyuk Jung, Tracy Yamawaki, et al.
Journal of Medicinal Chemistry
|
September 27, 2021
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
Jeffrey W Johannes, Amber Balazs, Derek Barratt, et al.
Journal of Medicinal Chemistry
|
January 27, 2025
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations
William McCoull, Clare Thomson, Erin Braybrooke, et al.
Nature Cancer
|
June 5, 2023
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
Thijs J Hagenbeek, Jason R Zbieg, Marc Hafner, et al.
Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|
April 27, 2019
Improved Outcomes Associated with the use of Shock Protocols: Updates from the National Cardiogenic Shock Initiative
Mir B Basir, Navin K Kapur, Kirit Patel, et al.
Journal of Medicinal Chemistry
|
January 9, 2014
Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymerase
Robert G Gentles, Min Ding, John A Bender, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
October 27, 2025
PI3Kα Inhibitor and Degrader Inavolisib Can Co-opt FGFR2 to Enhance Responses in Patients with PIK3CA-Mutated Solid Tumors and in Preclinical Models
Dejan Juric, Kyung Song, Radia M Johnson, et al.
Nature Communications
|
June 27, 2026
Covalent pan-TEAD inhibitors block YAP activity and demonstrate brain penetrance in a Hippo-dependent cancer model
Thijs J Hagenbeek, Jason Zbieg, Russell Smith, et al.
Page
of 25