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Scott P Runyon

Showing results (21-30 of 50) with videos related to

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Neuropharmacology|March 8, 2017
Identification of the first biased NPS receptor agonist that retains anxiolytic and memory promoting effects with reduced levels of locomotor stimulationStewart D Clark, Terrence P Kenakin, Steven Gertz, et al.
Journal of Medicinal Chemistry|March 11, 2021
Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in MiceSanju Narayanan, Shaobin Wang, Vineetha Vasukuttan, et al.
Bioorganic & Medicinal Chemistry|July 3, 2016
Discovery of a novel small molecule agonist scaffold for the APJ receptorSanju Narayanan, Rangan Maitra, Jeffery R Deschamps, et al.
Bioorganic & Medicinal Chemistry|July 29, 2015
The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptorDavid A Perrey, Ann M Decker, Jun-Xu Li, et al.
ACS Chemical Neuroscience|June 26, 2014
Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluationCarla Hassler, Yanan Zhang, Brian Gilmour, et al.
The Journal of Organic Chemistry|July 28, 2016
Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor AntagonistsScott P Runyon, Chad M Kormos, Moses G Gichinga, et al.
Bioorganic & Medicinal Chemistry|May 20, 2022
Synthesis and characterization of an orally bioavailable small molecule agonist of the apelin receptorSanju Narayanan, Donghua Dai, Ravi Kumar Vyas Devambatla, et al.
Journal of Medicinal Chemistry|June 24, 2010
Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activityScott P Runyon, Lawrence E Brieaddy, S Wayne Mascarella, et al.
Bioorganic & Medicinal Chemistry|July 2, 2016
Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteresChad M Kormos, Moses G Gichinga, Scott P Runyon, et al.
ACS Medicinal Chemistry Letters|July 26, 2017
Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor AntagonistsChad M Kormos, Pauline W Ondachi, Scott P Runyon, et al.
Pageof 5

Showing results (21-30 of 50) with videos related to

Sort By:
Pageof 5
Neuropharmacology|March 8, 2017
Identification of the first biased NPS receptor agonist that retains anxiolytic and memory promoting effects with reduced levels of locomotor stimulationStewart D Clark, Terrence P Kenakin, Steven Gertz, et al.
Journal of Medicinal Chemistry|March 11, 2021
Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in MiceSanju Narayanan, Shaobin Wang, Vineetha Vasukuttan, et al.
Bioorganic & Medicinal Chemistry|July 3, 2016
Discovery of a novel small molecule agonist scaffold for the APJ receptorSanju Narayanan, Rangan Maitra, Jeffery R Deschamps, et al.
Bioorganic & Medicinal Chemistry|July 29, 2015
The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptorDavid A Perrey, Ann M Decker, Jun-Xu Li, et al.
ACS Chemical Neuroscience|June 26, 2014
Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluationCarla Hassler, Yanan Zhang, Brian Gilmour, et al.
The Journal of Organic Chemistry|July 28, 2016
Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor AntagonistsScott P Runyon, Chad M Kormos, Moses G Gichinga, et al.
Bioorganic & Medicinal Chemistry|May 20, 2022
Synthesis and characterization of an orally bioavailable small molecule agonist of the apelin receptorSanju Narayanan, Donghua Dai, Ravi Kumar Vyas Devambatla, et al.
Journal of Medicinal Chemistry|June 24, 2010
Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activityScott P Runyon, Lawrence E Brieaddy, S Wayne Mascarella, et al.
Bioorganic & Medicinal Chemistry|July 2, 2016
Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteresChad M Kormos, Moses G Gichinga, Scott P Runyon, et al.
ACS Medicinal Chemistry Letters|July 26, 2017
Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor AntagonistsChad M Kormos, Pauline W Ondachi, Scott P Runyon, et al.
Pageof 5