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Current Opinion in Drug Discovery & Development
|
June 13, 2002
Structural genomics: bridging functional genomics and structure-based drug design
Sean G Buchanan
Oncotarget
|
January 11, 2019
Unraveling the genomic determinants of response to CDK4/6 inhibitors
Lacey M Litchfield, Vue W Webster, Sean G Buchanan
Cancer Research
|
July 21, 2010
MET kinase inhibitor SGX523 synergizes with epidermal growth factor receptor inhibitor erlotinib in a hepatocyte growth factor-dependent fashion to suppress carcinoma growth
Yu-Wen Zhang, Ben Staal, Curt Essenburg, et al.
Molecular Cancer Therapeutics
|
August 15, 2014
The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation
Vipin Yadav, Teresa F Burke, Lysiane Huber, et al.
Structure (London, England : 1993)
|
November 14, 2002
Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme
Brian W Noland, Janet M Newman, Jörg Hendle, et al.
Oncotarget
|
May 12, 2020
Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells
Lacey M Litchfield, Karsten Boehnke, Manisha Brahmachary, et al.
Nature Cancer
|
September 27, 2021
Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders
Xuewei Wu, Xiaobao Yang, Yan Xiong, et al.
The Journal of Biological Chemistry
|
October 28, 2004
A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase
Shane Atwell, Jason M Adams, John Badger, et al.
The EMBO Journal
|
December 20, 2003
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator
Hal A Lewis, Sean G Buchanan, Stephen K Burley, et al.
Investigational New Drugs
|
January 1, 2013
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models
S Betty Yan, Victoria L Peek, Rose Ajamie, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 16) with videos related to
Sort By:
Page
of 2
Current Opinion in Drug Discovery & Development
|
June 13, 2002
Structural genomics: bridging functional genomics and structure-based drug design
Sean G Buchanan
Oncotarget
|
January 11, 2019
Unraveling the genomic determinants of response to CDK4/6 inhibitors
Lacey M Litchfield, Vue W Webster, Sean G Buchanan
Cancer Research
|
July 21, 2010
MET kinase inhibitor SGX523 synergizes with epidermal growth factor receptor inhibitor erlotinib in a hepatocyte growth factor-dependent fashion to suppress carcinoma growth
Yu-Wen Zhang, Ben Staal, Curt Essenburg, et al.
Molecular Cancer Therapeutics
|
August 15, 2014
The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation
Vipin Yadav, Teresa F Burke, Lysiane Huber, et al.
Structure (London, England : 1993)
|
November 14, 2002
Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme
Brian W Noland, Janet M Newman, Jörg Hendle, et al.
Oncotarget
|
May 12, 2020
Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells
Lacey M Litchfield, Karsten Boehnke, Manisha Brahmachary, et al.
Nature Cancer
|
September 27, 2021
Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders
Xuewei Wu, Xiaobao Yang, Yan Xiong, et al.
The Journal of Biological Chemistry
|
October 28, 2004
A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase
Shane Atwell, Jason M Adams, John Badger, et al.
The EMBO Journal
|
December 20, 2003
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator
Hal A Lewis, Sean G Buchanan, Stephen K Burley, et al.
Investigational New Drugs
|
January 1, 2013
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models
S Betty Yan, Victoria L Peek, Rose Ajamie, et al.
Page
of 2