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ACS Pharmacology & Translational Science
|
March 21, 2022
Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators
Yan-Ling Zhang, Sean P Moran, Andrew Allen, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
March 28, 2018
M<sub>1</sub>-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
Sean P Moran, Jonathan W Dickerson, Hyekyung P Cho, et al.
Elife
|
May 26, 2022
Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells
Wenyang Li, Jennifer Y Chen, Cheng Sun, et al.
ACS Chemical Neuroscience
|
September 13, 2016
Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M<sub>1</sub> PAM VU6004256
Michael D Grannan, Catharine A Mielnik, Sean P Moran, et al.
Nature Cell Biology
|
September 8, 2020
lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation
Kaveh Daneshvar, M Behfar Ardehali, Isaac A Klein, et al.
Cell Reports
|
May 26, 2026
Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia
Sameer Aryal, Chuhan Geng, Margaret A Yin, et al.
ACS Chemical Neuroscience
|
April 28, 2018
A Novel M<sub>1</sub> PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity
Jerri M Rook, Jeanette L Bertron, Hyekyung P Cho, et al.
ACS Chemical Neuroscience
|
August 28, 2024
Discovery of VU6007496: Challenges in the Development of an M<sub>1</sub> Positive Allosteric Modulator Backup Candidate
Julie L Engers, Katrina A Bollinger, Rory A Capstick, et al.
Neuron
|
September 1, 2023
Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
Zohreh Farsi, Ally Nicolella, Sean K Simmons, et al.
Aging Brain
|
January 2, 2023
Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey
Anthony W S Chan, In Ki Cho, Chun-Xia Li, et al.
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Showing results (11-20 of 22) with videos related to
Sort By:
Page
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ACS Pharmacology & Translational Science
|
March 21, 2022
Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators
Yan-Ling Zhang, Sean P Moran, Andrew Allen, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
March 28, 2018
M<sub>1</sub>-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
Sean P Moran, Jonathan W Dickerson, Hyekyung P Cho, et al.
Elife
|
May 26, 2022
Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells
Wenyang Li, Jennifer Y Chen, Cheng Sun, et al.
ACS Chemical Neuroscience
|
September 13, 2016
Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M<sub>1</sub> PAM VU6004256
Michael D Grannan, Catharine A Mielnik, Sean P Moran, et al.
Nature Cell Biology
|
September 8, 2020
lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation
Kaveh Daneshvar, M Behfar Ardehali, Isaac A Klein, et al.
Cell Reports
|
May 26, 2026
Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia
Sameer Aryal, Chuhan Geng, Margaret A Yin, et al.
ACS Chemical Neuroscience
|
April 28, 2018
A Novel M<sub>1</sub> PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity
Jerri M Rook, Jeanette L Bertron, Hyekyung P Cho, et al.
ACS Chemical Neuroscience
|
August 28, 2024
Discovery of VU6007496: Challenges in the Development of an M<sub>1</sub> Positive Allosteric Modulator Backup Candidate
Julie L Engers, Katrina A Bollinger, Rory A Capstick, et al.
Neuron
|
September 1, 2023
Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
Zohreh Farsi, Ally Nicolella, Sean K Simmons, et al.
Aging Brain
|
January 2, 2023
Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey
Anthony W S Chan, In Ki Cho, Chun-Xia Li, et al.
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of 3