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Biochemistry|May 17, 2011
A combinatorial approach to engineering a dual-specific metal switch antibodySean W Fanning, Megan L Murtaugh, James R Horn
Protein Science : a Publication of the Protein Society|July 19, 2011
A combinatorial histidine scanning library approach to engineer highly pH-dependent protein switchesMegan L Murtaugh, Sean W Fanning, Tressa M Sharma, et al.
Protein Science : a Publication of the Protein Society|May 11, 2011
An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loopSean W Fanning, James R Horn
Protein Engineering, Design & Selection : PEDS|August 22, 2014
Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding siteSean W Fanning, Richard Walter, James R Horn
Virus Research|October 20, 2012
Mutations in the coat protein-binding cis-acting RNA motifs debilitate RNA recombination of Brome mosaic virusJoanna Sztuba-Solińska, Sean W Fanning, James R Horn, et al.
Endocrinology|February 13, 2019
Next-Generation ERα Inhibitors for Endocrine-Resistant ER+ Breast CancerSean W Fanning, Geoffrey L Greene
Endocrinology|April 21, 2024
Estrogen Receptor Alpha Mutations, Truncations, Heterodimers, and TherapiesGovinda R Hancock, Jason Gertz, Rinath Jeselsohn, et al.
Biochimica Et Biophysica Acta. Reviews on Cancer|November 6, 2022
ESR1 activating mutations: From structure to clinical applicationAlbert Grinshpun, Vincent Chen, Zachary M Sandusky, et al.
Methods in Molecular Biology (Clifton, N.J.)|February 14, 2022
Engineering pH-Sensitive Single-Domain AntibodiesTosha M Laughlin, James R Horn
Journal of Molecular Biology|March 24, 2004
Allosteric inhibition through core disruptionJames R Horn, Brian K Shoichet
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