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Sebastian Frechen

Showing results (11-20 of 42) with videos related to

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Drug Metabolism and Pharmacokinetics|November 30, 2015
Population pharmacokinetic and pharmacodynamic modeling of epinephrine administered using a mobile inhalerSebastian Frechen, Ahmed Abbas Suleiman, Ali Mohammad Nejad Sigaroudi, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|July 4, 2025
Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguatPaul Vrenken, Maria Vertzoni, Sebastian Frechen, et al.
CPT: Pharmacometrics & Systems Pharmacology|August 10, 2018
PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and DigoxinNina Hanke, Sebastian Frechen, Daniel Moj, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|June 12, 2025
Development of a novel Physiologically Based Biopharmaceutics modeling (PBBM) framework using the Open Systems Pharmacology Suite, Part 1: in vitro modeling of VericiguatPaul Vrenken, Maria Vertzoni, Sebastian Frechen, et al.
The Journal of Antimicrobial Chemotherapy|May 26, 2017
Optimization of linezolid therapy in the critically ill: the effect of adjusted infusion regimensMax Taubert, Johannes Zander, Sebastian Frechen, et al.
CPT: Pharmacometrics & Systems Pharmacology|May 4, 2021
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactionsSebastian Frechen, Juri Solodenko, Thomas Wendl, et al.
Clinical Pharmacokinetics|May 27, 2019
Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and ItraconazoleDenise Türk, Nina Hanke, Sarah Wolf, et al.
The AAPS Journal|November 9, 2016
Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication RegimensDaniel Moj, Nina Hanke, Hannah Britz, et al.
Clinical Pharmacology and Therapeutics|December 18, 2023
Assessment of the CYP3A4 Induction Potential by Carbamazepine: Insights from Two Clinical DDI Studies and PBPK ModelingFriederike Kanefendt, André Dallmann, Huijun Chen, et al.
Journal of Clinical Pharmacology|September 11, 2019
Predictive Pediatric Modeling and Simulation Using Ontogeny InformationIbrahim Ince, Juri Solodenko, Sebastian Frechen, et al.
Pageof 5

Showing results (11-20 of 42) with videos related to

Sort By:
Pageof 5
Drug Metabolism and Pharmacokinetics|November 30, 2015
Population pharmacokinetic and pharmacodynamic modeling of epinephrine administered using a mobile inhalerSebastian Frechen, Ahmed Abbas Suleiman, Ali Mohammad Nejad Sigaroudi, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|July 4, 2025
Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguatPaul Vrenken, Maria Vertzoni, Sebastian Frechen, et al.
CPT: Pharmacometrics & Systems Pharmacology|August 10, 2018
PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and DigoxinNina Hanke, Sebastian Frechen, Daniel Moj, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|June 12, 2025
Development of a novel Physiologically Based Biopharmaceutics modeling (PBBM) framework using the Open Systems Pharmacology Suite, Part 1: in vitro modeling of VericiguatPaul Vrenken, Maria Vertzoni, Sebastian Frechen, et al.
The Journal of Antimicrobial Chemotherapy|May 26, 2017
Optimization of linezolid therapy in the critically ill: the effect of adjusted infusion regimensMax Taubert, Johannes Zander, Sebastian Frechen, et al.
CPT: Pharmacometrics & Systems Pharmacology|May 4, 2021
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactionsSebastian Frechen, Juri Solodenko, Thomas Wendl, et al.
Clinical Pharmacokinetics|May 27, 2019
Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and ItraconazoleDenise Türk, Nina Hanke, Sarah Wolf, et al.
The AAPS Journal|November 9, 2016
Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication RegimensDaniel Moj, Nina Hanke, Hannah Britz, et al.
Clinical Pharmacology and Therapeutics|December 18, 2023
Assessment of the CYP3A4 Induction Potential by Carbamazepine: Insights from Two Clinical DDI Studies and PBPK ModelingFriederike Kanefendt, André Dallmann, Huijun Chen, et al.
Journal of Clinical Pharmacology|September 11, 2019
Predictive Pediatric Modeling and Simulation Using Ontogeny InformationIbrahim Ince, Juri Solodenko, Sebastian Frechen, et al.
Pageof 5