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European Journal of Cancer (Oxford, England : 1990)|October 29, 2021
HER2 mediates clinical resistance to the KRAS<sup>G12C</sup> inhibitor sotorasib, which is overcome by co-targeting SHP2Cassandra S L Ho, Alicia I Tüns, Hans-Ulrich Schildhaus, et al.
Nature|June 5, 2020
Oncometabolites suppress DNA repair by disrupting local chromatin signallingParker L Sulkowski, Sebastian Oeck, Jonathan Dow, et al.
Cells|April 9, 2020
Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End JoiningKlaudia Szymonowicz, Adam Krysztofiak, Jansje van der Linden, et al.
Angewandte Chemie (International Ed. in English)|June 26, 2015
Covalent-Allosteric Kinase InhibitorsJörn Weisner, Rajesh Gontla, Leandi van der Westhuizen, et al.
Nature Genetics|July 18, 2018
Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repairParker L Sulkowski, Ranjini K Sundaram, Sebastian Oeck, et al.
Nature Metabolism|May 13, 2020
Mitochondrial DNA Stress Signalling Protects the Nuclear GenomeZheng Wu, Sebastian Oeck, A Phillip West, et al.
Biochemical Pharmacology|December 7, 2020
Differential immunomodulatory effect of PARP inhibition in BRCA1 deficient and competent tumor cellsIsabel Alvarado-Cruz, Mariam Mahmoud, Mohammed Khan, et al.
Cell Reports|November 24, 2021
Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisMadeleine Dorsch, Manuela Kowalczyk, Mélanie Planque, et al.
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