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Sebastian Polak

Showing results (21-30 of 105) with videos related to

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Journal of Applied Toxicology : JAT|August 12, 2024
Physiologically-based pharmacokinetic model of in vitro porcine ear skin permeation for drug delivery researchLaura Krumpholz, Sebastian Polak, Barbara Wiśniowska
Clinical Pharmacology and Therapeutics|April 26, 2024
How PBPK Can Help to Understand Old Drugs and Inform their Dosing in Elderly: Amantadine Case StudyOlha Shuklinova, Sibylle Neuhoff, Sebastian Polak
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|October 22, 2024
Towards the understanding of the IVPT results variability-Development, verification and validation of the PBPK model of caffeine in vitro human skin permeationLaura Krumpholz, Sebastian Polak, Barbara Wiśniowska
Journal of Pharmaceutical Sciences|November 28, 2017
Mechanistic Physiologically Based Pharmacokinetic (PBPK) Model of the Heart Accounting for Inter-Individual Variability: Development and Performance VerificationZofia Tylutki, Aleksander Mendyk, Sebastian Polak
The AAPS Journal|July 12, 2018
Virtual Thorough QT (TQT) Trial-Extrapolation of In Vitro Cardiac Safety Data to In Vivo Situation Using Multi-Scale Physiologically Based Ventricular Cell-wall Model Exemplified with Tolterodine and FesoterodineNikunjkumar Patel, Barbara Wisniowska, Sebastian Polak
Journal of Pharmacokinetics and Pharmacodynamics|June 27, 2018
Physiologically based pharmacokinetic-quantitative systems toxicology and safety (PBPK-QSTS) modeling approach applied to predict the variability of amitriptyline pharmacokinetics and cardiac safety in populations and in individualsZofia Tylutki, Aleksander Mendyk, Sebastian Polak
Journal of Applied Toxicology : JAT|November 7, 2008
Collation, assessment and analysis of literature in vitro data on hERG receptor blocking potency for subsequent modeling of drugs' cardiotoxic propertiesSebastian Polak, Barbara Wiśniowska, Jerzy Brandys
Data in Brief|April 15, 2024
Dataset of in vitro measured chemicals neurotoxicitySeweryn Ulaszek, Bartek Lisowski, Sebastian Polak
Frontiers in Physiology|October 7, 2017
Humans Vary, So Cardiac Models Should Account for That Too!Barbara Wiśniowska, Zofia Tylutki, Sebastian Polak
Drug Discovery Today|May 18, 2017
Thorough QT (TQT) studies: concordance with torsadogenesis and an evolving cardiac safety testing paradigmBarbara Wiśniowska, Zofia Tylutki, Sebastian Polak
Pageof 11

Showing results (21-30 of 105) with videos related to

Sort By:
Pageof 11
Journal of Applied Toxicology : JAT|August 12, 2024
Physiologically-based pharmacokinetic model of in vitro porcine ear skin permeation for drug delivery researchLaura Krumpholz, Sebastian Polak, Barbara Wiśniowska
Clinical Pharmacology and Therapeutics|April 26, 2024
How PBPK Can Help to Understand Old Drugs and Inform their Dosing in Elderly: Amantadine Case StudyOlha Shuklinova, Sibylle Neuhoff, Sebastian Polak
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|October 22, 2024
Towards the understanding of the IVPT results variability-Development, verification and validation of the PBPK model of caffeine in vitro human skin permeationLaura Krumpholz, Sebastian Polak, Barbara Wiśniowska
Journal of Pharmaceutical Sciences|November 28, 2017
Mechanistic Physiologically Based Pharmacokinetic (PBPK) Model of the Heart Accounting for Inter-Individual Variability: Development and Performance VerificationZofia Tylutki, Aleksander Mendyk, Sebastian Polak
The AAPS Journal|July 12, 2018
Virtual Thorough QT (TQT) Trial-Extrapolation of In Vitro Cardiac Safety Data to In Vivo Situation Using Multi-Scale Physiologically Based Ventricular Cell-wall Model Exemplified with Tolterodine and FesoterodineNikunjkumar Patel, Barbara Wisniowska, Sebastian Polak
Journal of Pharmacokinetics and Pharmacodynamics|June 27, 2018
Physiologically based pharmacokinetic-quantitative systems toxicology and safety (PBPK-QSTS) modeling approach applied to predict the variability of amitriptyline pharmacokinetics and cardiac safety in populations and in individualsZofia Tylutki, Aleksander Mendyk, Sebastian Polak
Journal of Applied Toxicology : JAT|November 7, 2008
Collation, assessment and analysis of literature in vitro data on hERG receptor blocking potency for subsequent modeling of drugs' cardiotoxic propertiesSebastian Polak, Barbara Wiśniowska, Jerzy Brandys
Data in Brief|April 15, 2024
Dataset of in vitro measured chemicals neurotoxicitySeweryn Ulaszek, Bartek Lisowski, Sebastian Polak
Frontiers in Physiology|October 7, 2017
Humans Vary, So Cardiac Models Should Account for That Too!Barbara Wiśniowska, Zofia Tylutki, Sebastian Polak
Drug Discovery Today|May 18, 2017
Thorough QT (TQT) studies: concordance with torsadogenesis and an evolving cardiac safety testing paradigmBarbara Wiśniowska, Zofia Tylutki, Sebastian Polak
Pageof 11