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Toxicological Sciences : an Official Journal of the Society of Toxicology
|
May 31, 2018
Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2'-MOE-Modified Antisense Oligonucleotide
Padmakumar Narayanan, Lijiang Shen, Brian R Curtis, et al.
Nucleic Acid Therapeutics
|
May 23, 2013
Preclinical evaluation of the toxicological effects of a novel constrained ethyl modified antisense compound targeting signal transducer and activator of transcription 3 in mice and cynomolgus monkeys
Sebastien A Burel, So-Ri Han, Hong-Soo Lee, et al.
Nucleic Acid Therapeutics
|
February 12, 2020
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia
PadmaKumar Narayanan, Brian R Curtis, Lijiang Shen, et al.
Nucleic Acids Research
|
August 21, 2021
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides
Brooke A Anderson, Graeme C Freestone, Audrey Low, et al.
Nucleic Acids Research
|
November 11, 2015
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts
Sebastien A Burel, Christopher E Hart, Patrick Cauntay, et al.
Journal of Medicinal Chemistry
|
February 26, 2016
Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes
Thazha P Prakash, Jinghua Yu, Michael T Migawa, et al.
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of 2
Search research articles
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Showing results (11-20 of 16) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 16 results.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
May 31, 2018
Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2'-MOE-Modified Antisense Oligonucleotide
Padmakumar Narayanan, Lijiang Shen, Brian R Curtis, et al.
Nucleic Acid Therapeutics
|
May 23, 2013
Preclinical evaluation of the toxicological effects of a novel constrained ethyl modified antisense compound targeting signal transducer and activator of transcription 3 in mice and cynomolgus monkeys
Sebastien A Burel, So-Ri Han, Hong-Soo Lee, et al.
Nucleic Acid Therapeutics
|
February 12, 2020
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia
PadmaKumar Narayanan, Brian R Curtis, Lijiang Shen, et al.
Nucleic Acids Research
|
August 21, 2021
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides
Brooke A Anderson, Graeme C Freestone, Audrey Low, et al.
Nucleic Acids Research
|
November 11, 2015
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts
Sebastien A Burel, Christopher E Hart, Patrick Cauntay, et al.
Journal of Medicinal Chemistry
|
February 26, 2016
Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes
Thazha P Prakash, Jinghua Yu, Michael T Migawa, et al.
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of 2