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The Journal of Steroid Biochemistry and Molecular Biology|May 7, 2005
The antagonism between 2-methyl-1,25-dihydroxyvitamin D3 and 2-methyl-20-epi-1,25-dihydroxyvitamin D3 in non-genomic pathway-mediated biological responses induced by 1alpha,25-dihydroxyvitamin D3 assessed by NB4 cell differentiationDaishiro Miura, Anthony W Norman, Mathew T Mizwicki, et al.Molecular Endocrinology (Baltimore, Md.)|January 15, 2005
Molecular mechanism of the vitamin D antagonistic actions of (23S)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone depends on the primary structure of the carboxyl-terminal region of the vitamin d receptorEiji Ochiai, Daishiro Miura, Hiroshi Eguchi, et al.Journal of Medicinal Chemistry|November 28, 2006
Further synthetic and biological studies on vitamin D hormone antagonists based on C24-alkylation and C2alpha-functionalization of 25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactonesNozomi Saito, Toshihiro Matsunaga, Hiroshi Saito, et al.Organic & Biomolecular Chemistry|December 20, 2003
Remarkable effect of 2[small alpha]-modification on the VDR antagonistic activity of 1small alpha-hydroxyvitamin D3-26,23-lactonesNozomi Saito, Toshihiro Matsunaga, Toshie Fujishima, et al.The Journal of Steroid Biochemistry and Molecular Biology|January 16, 2007
Creative synthesis of novel vitamin D analogs for health and diseaseAtsushi Kittaka, Nozomi Saito, Shinobu Honzawa, et al.Organic Letters|December 5, 2003
Dramatic enhancement of antagonistic activity on vitamin D receptor: a double functionalization of 1alpha-hydroxyvitamin D3 26,23-lactonesNozomi Saito, Hiroshi Saito, Miyuki Anzai, et al.Journal of Medicinal Chemistry|April 14, 2006
Practical synthesis and evaluation of the biological activities of 1alpha,25-dihydroxyvitamin D3 antagonists, 1alpha,25-dihydroxyvitamin D3-26,23-lactams. Designed on the basis of the helix 12-folding inhibition hypothesisYusuke Nakano, Yuko Kato, Keisuke Imai, et al.Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research|June 5, 2004
Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's DiseaseNoriyoshi Kurihara, Sakamuri V Reddy, Norie Araki, et al.Bioorganic & Medicinal Chemistry Letters|August 21, 2009
Synthesis of 2alpha-substituted-14-epi-previtamin D3 and its genomic activityDaisuke Sawada, Tomoyuki Katayama, Yuya Tsukuda, et al.Archives of Biochemistry and Biophysics|October 19, 2004
C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1Norbert Astecker, Ekaterina A Bobrovnikova, John L Omdahl, et al.Pageof 3