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Biochemical Pharmacology|April 15, 2017
Repurposing bacterial toxins for intracellular delivery of therapeutic proteinsGreg L Beilhartz, Seiji N Sugiman-Marangos, Roman A Melnyk
Proceedings of the National Academy of Sciences of the United States of America|April 5, 2016
Mechanism for accurate, protein-assisted DNA annealing by Deinococcus radiodurans DdrBSeiji N Sugiman-Marangos, Yoni M Weiss, Murray S Junop
Critical Reviews in Biochemistry and Molecular Biology|May 27, 2017
Clostridium difficile toxins A and B: Receptors, pores, and translocation into cellsKathleen E Orrell, Zhifen Zhang, Seiji N Sugiman-Marangos, et al.
FEBS Letters|July 31, 2018
Identification of a diphtheria toxin-like gene family beyond the Corynebacterium genusMichael J Mansfield, Seiji N Sugiman-Marangos, Roman A Melnyk, et al.
Nucleic Acids Research|August 27, 2013
Crystal structure of the DdrB/ssDNA complex from Deinococcus radiodurans reveals a DNA binding surface involving higher-order oligomeric statesSeiji N Sugiman-Marangos, John K Peel, Yoni M Weiss, et al.
EMBO Molecular Medicine|August 19, 2024
An enhanced intracellular delivery platform based on a distant diphtheria toxin homolog that evades pre-existing antitoxin antibodiesShivneet K Gill, Seiji N Sugiman-Marangos, Greg L Beilhartz, et al.
Communications Biology|April 20, 2022
Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffoldSeiji N Sugiman-Marangos, Shivneet K Gill, Michael J Mansfield, et al.
Molecular Pharmaceutics|September 14, 2018
Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target CellsMinyoung Park, Xiaobai Xu, Weixian Min, et al.
Science Advances|December 14, 2020
Exploiting the diphtheria toxin internalization receptor enhances delivery of proteins to lysosomes for enzyme replacement therapySeiji N Sugiman-Marangos, Greg L Beilhartz, Xiaochu Zhao, et al.
Journal of Bacteriology|June 15, 2016
The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent FunctionsRyan N C Buensuceso, Ylan Nguyen, Kun Zhang, et al.
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