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Oncogene|July 2, 2026
Amphiregulin-mediated EGFR activation drives both intrinsic and acquired resistance to KRAS G12C inhibitors in KRAS G12C-mutant non-small cell lung cancerYifeng Liu, Shigeki Nanjo, Yuya Murase, et al.The Journal of Medical Investigation : JMI|September 18, 2010
Epidemiological and clinical features of lung cancer patients from 1999 to 2009 in Tokushima Prefecture of JapanTakanori Kanematsu, Masaki Hanibuchi, Hideki Tomimoto, et al.Translational Lung Cancer Research|December 13, 2024
EGFR-V834L combined with L858R mutation reduced afatinib sensitivity and associated to early recurrence in lung cancerNanao Terada, Hayato Koba, Shigeki Nanjo, et al.Nature Communications|January 18, 2019
AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cellsHirokazu Taniguchi, Tadaaki Yamada, Rong Wang, et al.Cancer Science|January 18, 2026
Therapeutic Strategies to Overcome Payload Resistance of Trastuzumab Deruxtecan in HER2-Positive CancersYuya Murase, Shigeki Nanjo, Sachiko Arai, et al.Translational Lung Cancer Research|September 29, 2021
Impact of tumor programmed death ligand-1 expression on osimertinib efficacy in untreated EGFR-mutated advanced non-small cell lung cancer: a prospective observational studyAkihiro Yoshimura, Tadaaki Yamada, Yusuke Okuma, et al.NPJ Precision Oncology|January 19, 2022
HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal featuresKeiko Tanimura, Tadaaki Yamada, Koutaroh Okada, et al.Cancer Letters|February 11, 2024
AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cellsKenji Morimoto, Tadaaki Yamada, Soichi Hirai, et al.Nature Communications|September 15, 2020
Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancerRong Wang, Tadaaki Yamada, Kenji Kita, et al.Nature Communications|August 12, 2018
Notch3-dependent β-catenin signaling mediates EGFR TKI drug persistence in EGFR mutant NSCLCRajeswara Rao Arasada, Konstantin Shilo, Tadaaki Yamada, et al.Pageof 29