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Mabs|July 5, 2023
Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodiesHan Ping Loh, Farouq Bin Mahfut, Serene W Chen, et al.
Journal of the American Chemical Society|March 12, 2016
Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox SilencingJeppe T Pedersen, Serene W Chen, Christian B Borg, et al.
Chemical Science|February 1, 2021
The extent of protein hydration dictates the preference for heterogeneous or homogeneous nucleation generating either parallel or antiparallel β-sheet α-synuclein aggregatesJosé D Camino, Pablo Gracia, Serene W Chen, et al.
Biochemistry|February 24, 2017
Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein SpeciesFrancesco A Aprile, Paolo Arosio, Giuliana Fusco, et al.
Journal of the American Chemical Society|April 3, 2024
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein CondensatesSerene W Chen, Joseph D Barritt, Roberta Cascella, et al.
Molecules (Basel, Switzerland)|February 25, 2022
The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular ToxicityCatherine K Xu, Marta Castellana-Cruz, Serene W Chen, et al.
Science (New York, N.Y.)|December 16, 2017
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomersGiuliana Fusco, Serene W Chen, Philip T F Williamson, et al.
The Journal of Biological Chemistry|May 31, 2019
Defining α-synuclein species responsible for Parkinson's disease phenotypes in miceJessica M Froula, Marta Castellana-Cruz, Nadia M Anabtawi, et al.
ACS Chemical Neuroscience|January 23, 2016
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human BiofluidsMathew H Horrocks, Steven F Lee, Sonia Gandhi, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 10, 2015
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formationSerene W Chen, Srdja Drakulic, Emma Deas, et al.
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