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Sergio C Chai

Showing results (31-40 of 51) with videos related to

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Toxicology and Applied Pharmacology|May 28, 2013
Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1Yue-Ming Wang, Wenwei Lin, Sergio C Chai, et al.
Journal of the American Chemical Society|December 22, 2010
Novel pyrrolopyrimidine-based α-helix mimetics: cell-permeable inhibitors of protein−protein interactionsJi Hoon Lee, Qi Zhang, Sunhwan Jo, et al.
The Journal of Biological Chemistry|December 30, 2004
Heterologous expression, purification, and characterization of recombinant rat cysteine dioxygenaseSergio C Chai, Ann A Jerkins, Jacob J Banik, et al.
Nature Communications|October 1, 2017
SPA70 is a potent antagonist of human pregnane X receptorWenwei Lin, Yue-Ming Wang, Sergio C Chai, et al.
Nature Communications|May 14, 2024
Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXREfren Garcia-Maldonado, Andrew D Huber, Sergio C Chai, et al.
Nature Communications|April 10, 2025
Decoding the selective chemical modulation of CYP3A4Jingheng Wang, Stanley Nithianantham, Sergio C Chai, et al.
Biochemical Pharmacology|April 3, 2018
CINPA1 binds directly to constitutive androstane receptor and inhibits its activityMilu T Cherian, Sergio C Chai, William C Wright, et al.
Journal of Medicinal Chemistry|January 23, 2020
Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5William C Wright, Jude Chenge, Jingheng Wang, et al.
Journal of the American Chemical Society|October 14, 2021
Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5Jingheng Wang, Cameron D Buchman, Jayaraman Seetharaman, et al.
Nucleic Acids Research|December 12, 2023
A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXRAndrew D Huber, Shyaron Poudel, Jing Wu, et al.
Pageof 6

Showing results (31-40 of 51) with videos related to

Sort By:
Pageof 6
Toxicology and Applied Pharmacology|May 28, 2013
Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1Yue-Ming Wang, Wenwei Lin, Sergio C Chai, et al.
Journal of the American Chemical Society|December 22, 2010
Novel pyrrolopyrimidine-based α-helix mimetics: cell-permeable inhibitors of protein−protein interactionsJi Hoon Lee, Qi Zhang, Sunhwan Jo, et al.
The Journal of Biological Chemistry|December 30, 2004
Heterologous expression, purification, and characterization of recombinant rat cysteine dioxygenaseSergio C Chai, Ann A Jerkins, Jacob J Banik, et al.
Nature Communications|October 1, 2017
SPA70 is a potent antagonist of human pregnane X receptorWenwei Lin, Yue-Ming Wang, Sergio C Chai, et al.
Nature Communications|May 14, 2024
Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXREfren Garcia-Maldonado, Andrew D Huber, Sergio C Chai, et al.
Nature Communications|April 10, 2025
Decoding the selective chemical modulation of CYP3A4Jingheng Wang, Stanley Nithianantham, Sergio C Chai, et al.
Biochemical Pharmacology|April 3, 2018
CINPA1 binds directly to constitutive androstane receptor and inhibits its activityMilu T Cherian, Sergio C Chai, William C Wright, et al.
Journal of Medicinal Chemistry|January 23, 2020
Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5William C Wright, Jude Chenge, Jingheng Wang, et al.
Journal of the American Chemical Society|October 14, 2021
Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5Jingheng Wang, Cameron D Buchman, Jayaraman Seetharaman, et al.
Nucleic Acids Research|December 12, 2023
A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXRAndrew D Huber, Shyaron Poudel, Jing Wu, et al.
Pageof 6