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Science (New York, N.Y.)|January 5, 2023
Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammationMasayuki Hata, Elisabeth M M A Andriessen, Maki Hata, et al.Nature Communications|June 25, 2025
Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathyGael Cagnone, Sheetal Pundir, Charlotte Betus, et al.Cell Metabolism|February 6, 2021
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibitionSergio Crespo-Garcia, Pamela R Tsuruda, Agnieszka Dejda, et al.Nature Medicine|February 6, 2024
Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial resultsSergio Crespo-Garcia, Frédérik Fournier, Roberto Diaz-Marin, et al.Science (New York, N.Y.)|August 22, 2020
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathyFrançois Binet, Gael Cagnone, Sergio Crespo-Garcia, et al.Pageof 4