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The Journal of Pharmacology and Experimental Therapeutics|August 3, 2019
SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D<sub>2</sub> Receptor Mechanism of ActionNina Dedic, Philip G Jones, Seth C Hopkins, et al.
Sleep Medicine|December 30, 2022
Treatment with the novel TAAR1 agonist ulotaront is associated with reductions in quantitative polysomnographic REM sleep without atonia in healthy human subjects: Results of a post-hoc analysisJohn C Feemster, Sarah M Westerland, Thomas R Gossard, et al.
Journal of Molecular Biology|June 27, 2002
Orientation changes of the myosin light chain domain during filament sliding in active and rigor muscleSeth C Hopkins, Cibele Sabido-David, Uulke A van der Heide, et al.
Molecular Metabolism|January 18, 2024
TAAR1 agonists improve glycemic control, reduce body weight and modulate neurocircuits governing energy balance and feedingNina Dedic, Lien Wang, Eva Hajos-Korcsok, et al.
Schizophrenia (Heidelberg, Germany)|August 7, 2023
Effects of ulotaront on brain circuits of reward, working memory, and emotion processing in healthy volunteers with high or low schizotypyFrancesca Perini, Jadwiga Maria Nazimek, Shane Mckie, et al.
Biological Psychiatry|June 28, 2024
Mesostriatal Dopaminergic Circuit Dysfunction in Schizophrenia: A Multimodal Neuromelanin-Sensitive Magnetic Resonance Imaging and [<sup>18</sup>F]-DOPA Positron Emission Tomography StudyLuke J Vano, Robert A McCutcheon, Grazia Rutigliano, et al.
Molecular Psychiatry|May 9, 2020
Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamineMichelle Kokkinou, Elaine E Irvine, David R Bonsall, et al.
Clinical Pharmacology and Therapeutics|June 1, 2024
Discovery and Model-Informed Drug Development of a Controlled-Release Formulation of Nonracemic Amisulpride that Reduces Plasma Exposure but Achieves Pharmacodynamic Bioequivalence in the BrainSeth C Hopkins, Siriporn Toongsuwan, Taryn J Corriveau, et al.
Biological Psychiatry|October 23, 2025
The trace amine-associated receptor 1 regulates presynaptic dopamine function: evidence from preclinical studies and a phase 1b trial in patients with schizophreniaOliver D Howes, Luke J Vano, Alice E Petty, et al.
Journal of Medicinal Chemistry|May 2, 2013
Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small moleculesSeth C Hopkins, Michele L R Heffernan, Lakshmi D Saraswat, et al.
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