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Journal of Bacteriology|September 5, 2024
Differential effects of inosine monophosphate dehydrogenase (IMPDH/GuaB) inhibition in <i>Acinetobacter baumannii</i> and <i>Escherichia coli</i>Yutian Peng, John G Moffat, Cory DuPai, et al.Journal of Medicinal Chemistry|March 21, 2013
De novo fragment design: a medicinal chemistry approach to fragment-based lead generationFrancisco X Talamas, Gloria Ao-Ieong, Ken A Brameld, et al.Journal of Medicinal Chemistry|September 28, 2013
Discovery of a novel series of potent non-nucleoside inhibitors of hepatitis C virus NS5BRyan C Schoenfeld, David L Bourdet, Ken A Brameld, et al.Proceedings of the National Academy of Sciences of the United States of America|February 12, 2025
Impairment of DET1 causes neurological defects and lethality in mice and humansOzge Karayel, Allison Soung, Hem Gurung, et al.Journal of Medicinal Chemistry|March 29, 2014
Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimizationTerry D Crawford, Chudi O Ndubaku, Huifen Chen, et al.ACS Medicinal Chemistry Letters|August 20, 2015
Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal AngiogenesisChudi O Ndubaku, Terry D Crawford, Huifen Chen, et al.Mabs|June 4, 2019
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily membersYanli Yang, Sherry H Yeh, Shravan Madireddi, et al.Bioorganic & Medicinal Chemistry Letters|July 18, 2008
Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptaseZachary K Sweeney, James P Dunn, Yu Li, et al.Chemmedchem|November 14, 2008
Diphenyl ether non-nucleoside reverse transcriptase inhibitors with excellent potency against resistant mutant viruses and promising pharmacokinetic propertiesZachary K Sweeney, Joshua J Kennedy-Smith, Jeffrey Wu, et al.ACS Medicinal Chemistry Letters|April 16, 2020
Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase InhibitorsBrendan T Parr, Richard Pastor, Benjamin D Sellers, et al.Pageof 5