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Sethu Sankaranarayanan

Showing results (31-40 of 40) with videos related to

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Journal of Proteome Research|January 26, 2010
Application of an end-to-end biomarker discovery platform to identify target engagement markers in cerebrospinal fluid by high resolution differential mass spectrometryCloud P Paweletz, Matthew C Wiener, Andrey Y Bondarenko, et al.
Plos One|May 2, 2015
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy modelsSethu Sankaranarayanan, Donna M Barten, Laurel Vana, et al.
Chemmedchem|December 17, 2008
Evolution of tertiary carbinamine BACE-1 inhibitors: Abeta reduction in rhesus CSF upon oral dosingPhilippe G Nantermet, Hemaka A Rajapakse, Mathew G Stanton, et al.
Bioorganic & Medicinal Chemistry Letters|May 8, 2007
Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitorsStacey R Lindsley, Keith P Moore, Hemaka A Rajapakse, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|May 25, 2012
Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027Donna M Barten, Patrizia Fanara, Cathy Andorfer, et al.
Journal of Medicinal Chemistry|September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretaseJames C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.
Journal of Alzheimer'S Disease : JAD|April 27, 2005
Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cellsXiao-Ping Shi, Katherine Tugusheva, James E Bruce, et al.
Bioorganic & Medicinal Chemistry Letters|July 22, 2015
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potencyMelissa Egbertson, Georgia B McGaughey, Steven M Pitzenberger, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 1, 2013
Pharmacodynamics of selective inhibition of γ-secretase by avagacestatCharles F Albright, Randy C Dockens, Jere E Meredith, et al.
The Journal of Pharmacology and Experimental Therapeutics|October 16, 2008
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primatesSethu Sankaranarayanan, Marie A Holahan, Dennis Colussi, et al.
Pageof 4

Showing results (31-40 of 40) with videos related to

Sort By:
Pageof 4
You have reached the last page of results.This site can display upto 40 results.
Journal of Proteome Research|January 26, 2010
Application of an end-to-end biomarker discovery platform to identify target engagement markers in cerebrospinal fluid by high resolution differential mass spectrometryCloud P Paweletz, Matthew C Wiener, Andrey Y Bondarenko, et al.
Plos One|May 2, 2015
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy modelsSethu Sankaranarayanan, Donna M Barten, Laurel Vana, et al.
Chemmedchem|December 17, 2008
Evolution of tertiary carbinamine BACE-1 inhibitors: Abeta reduction in rhesus CSF upon oral dosingPhilippe G Nantermet, Hemaka A Rajapakse, Mathew G Stanton, et al.
Bioorganic & Medicinal Chemistry Letters|May 8, 2007
Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitorsStacey R Lindsley, Keith P Moore, Hemaka A Rajapakse, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|May 25, 2012
Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027Donna M Barten, Patrizia Fanara, Cathy Andorfer, et al.
Journal of Medicinal Chemistry|September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretaseJames C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.
Journal of Alzheimer'S Disease : JAD|April 27, 2005
Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cellsXiao-Ping Shi, Katherine Tugusheva, James E Bruce, et al.
Bioorganic & Medicinal Chemistry Letters|July 22, 2015
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potencyMelissa Egbertson, Georgia B McGaughey, Steven M Pitzenberger, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 1, 2013
Pharmacodynamics of selective inhibition of γ-secretase by avagacestatCharles F Albright, Randy C Dockens, Jere E Meredith, et al.
The Journal of Pharmacology and Experimental Therapeutics|October 16, 2008
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primatesSethu Sankaranarayanan, Marie A Holahan, Dennis Colussi, et al.
Pageof 4