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Combinatorial Chemistry & High Throughput Screening|April 23, 2002
A probabilistic approach to high throughput drug discoveryPaul Labute, Shahul Nilar, Christopher Williams
Journal of Computer-Aided Molecular Design|September 18, 2012
Extraction and validation of substructure profiles for enriching compound librariesWee Kiang Yeo, Mei Lin Go, Shahul Nilar
Advances in Experimental Medicine and Biology|May 31, 2018
Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided DesignSiew Pheng Lim, Christian G Noble, Shahul Nilar, et al.
The Journal of Biological Chemistry|February 14, 2016
A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based ScreeningChristian G Noble, Siew Pheng Lim, Rishi Arora, et al.
Bioorganic & Medicinal Chemistry Letters|July 1, 2024
The search for pyruvate kinase-R activators; from a HTS screening hit via an impurity to the discovery of a lead seriesChul Yu, Lina Quattrocchio Setti, Shahul Nilar, et al.
Antiviral Research|October 1, 2013
Ten years of dengue drug discovery: progress and prospectsSiew Pheng Lim, Qing-Yin Wang, Christian G Noble, et al.
Journal of Medicinal Chemistry|March 18, 2016
Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug DesignFumiaki Yokokawa, Shahul Nilar, Christian G Noble, et al.
Journal of Virology|March 19, 2010
Inhibition of dengue virus polymerase by blocking of the RNA tunnelPornwaratt Niyomrattanakit, Yen-Liang Chen, Hongping Dong, et al.
Antiviral Research|April 22, 2015
Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screeningPornwaratt Niyomrattanakit, Kah Fei Wan, Ka Yan Chung, et al.
Antimicrobial Agents and Chemotherapy|July 7, 2011
A translation inhibitor that suppresses dengue virus in vitro and in vivoQing-Yin Wang, Ravinder Reddy Kondreddi, Xuping Xie, et al.
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