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Molecular Cancer Therapeutics|June 19, 2003
Why target apoptosis in cancer treatment?Shailaja Kasibhatla, Ben TsengCurrent Medicinal Chemistry|October 5, 2006
A chemical genetics approach for the discovery of apoptosis inducers: from phenotypic cell based HTS assay and structure-activity relationship studies, to identification of potential anticancer agents and molecular targetsSui Xiong Cai, John Drewe, Shailaja KasibhatlaBioorganic & Medicinal Chemistry|June 10, 2004
Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assayHan-Zhong Zhang, John Drewe, Ben Tseng, et al.Bioorganic & Medicinal Chemistry|March 14, 2008
Synthesis of caged 2,3,3a,7a-tetrahydro-3,6-methanobenzofuran-7(6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acidJared Kuemmerle, Songchun Jiang, Ben Tseng, et al.Bioconjugate Chemistry|March 20, 2003
N-Ac-DEVD-N'-(Polyfluorobenzoyl)-R110: novel cell-permeable fluorogenic caspase substrates for the detection of caspase activity and apoptosisHan-Zhong Zhang, Shailaja Kasibhatla, John Guastella, et al.Bioorganic & Medicinal Chemistry Letters|June 9, 2009
Discovery of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers. 2. Identification of more aqueous soluble analogs as potential anticancer agentsWilliam Kemnitzer, Jared Kuemmerle, Han-Zhong Zhang, et al.Molecular and Cellular Biology|November 16, 2004
Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditionsJiang-Yan Yang, David Michod, Joël Walicki, et al.Bioorganic & Medicinal Chemistry Letters|December 26, 2009
Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 9-oxo-9H-fluorene ringWilliam Kemnitzer, Nilantha Sirisoma, Songchun Jiang, et al.Bioorganic & Medicinal Chemistry Letters|March 17, 2009
Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure-activity relationships of the 2-aryl groupNilantha Sirisoma, Azra Pervin, Bao Nguyen, et al.Bioorganic & Medicinal Chemistry|January 16, 2004
Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assayHan-Zhong Zhang, Shailaja Kasibhatla, Yan Wang, et al.Pageof 5