Shailaja Kasibhatla - JoVE Visualize

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Bioorganic & Medicinal Chemistry Letters|May 27, 2009

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positionsWilliam Kemnitzer, Jared Kuemmerle, Songchun Jiang, et al.

Bioorganic & Medicinal Chemistry|August 22, 2006

Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino groupNilantha Sirisoma, Shailaja Kasibhatla, Bao Nguyen, et al.

Journal of Medicinal Chemistry|May 30, 2003

Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assaySui Xiong Cai, Bao Nguyen, Shaojuan Jia, et al.

Bioorganic & Medicinal Chemistry Letters|April 28, 2009

Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the carboxamide groupWilliam Kemnitzer, Nilantha Sirisoma, Bao Nguyen, et al.

Cancer Letters|November 15, 2008

Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2(1H)-quinolinones through a Myc-dependent pathwayGisela Claassen, Elena Brin, Candace Crogan-Grundy, et al.

Bioorganic & Medicinal Chemistry Letters|June 15, 2007

Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assayJohn Drewe, Shailaja Kasibhatla, Ben Tseng, et al.

Bioorganic & Medicinal Chemistry Letters|October 28, 2008

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positionsWilliam Kemnitzer, Jared Kuemmerle, Songchun Jiang, et al.

Journal of Medicinal Chemistry|August 5, 2005

Discovery and structure-activity relationship of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers and potential anticancer agentsHan-Zhong Zhang, Shailaja Kasibhatla, Jared Kuemmerle, et al.

British Journal of Pharmacology|September 13, 2003

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activityWu Yang, John Guastella, Jin-Cheng Huang, et al.

The AAPS Journal|August 28, 2021

Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding StudiesRoberto A Abbiati, Michael Pourdehnad, Soraya Carrancio, et al.

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Bioorganic & Medicinal Chemistry Letters|May 27, 2009

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positionsWilliam Kemnitzer, Jared Kuemmerle, Songchun Jiang, et al.

Bioorganic & Medicinal Chemistry|August 22, 2006

Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino groupNilantha Sirisoma, Shailaja Kasibhatla, Bao Nguyen, et al.

Journal of Medicinal Chemistry|May 30, 2003

Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assaySui Xiong Cai, Bao Nguyen, Shaojuan Jia, et al.

Bioorganic & Medicinal Chemistry Letters|April 28, 2009

Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the carboxamide groupWilliam Kemnitzer, Nilantha Sirisoma, Bao Nguyen, et al.

Cancer Letters|November 15, 2008

Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2(1H)-quinolinones through a Myc-dependent pathwayGisela Claassen, Elena Brin, Candace Crogan-Grundy, et al.

Bioorganic & Medicinal Chemistry Letters|June 15, 2007

Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assayJohn Drewe, Shailaja Kasibhatla, Ben Tseng, et al.

Bioorganic & Medicinal Chemistry Letters|October 28, 2008

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positionsWilliam Kemnitzer, Jared Kuemmerle, Songchun Jiang, et al.

Journal of Medicinal Chemistry|August 5, 2005

Discovery and structure-activity relationship of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers and potential anticancer agentsHan-Zhong Zhang, Shailaja Kasibhatla, Jared Kuemmerle, et al.

British Journal of Pharmacology|September 13, 2003

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activityWu Yang, John Guastella, Jin-Cheng Huang, et al.

The AAPS Journal|August 28, 2021

Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding StudiesRoberto A Abbiati, Michael Pourdehnad, Soraya Carrancio, et al.

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