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Elife|December 9, 2021
A helicase-tethered ORC flip enables bidirectional helicase loadingShalini Gupta, Larry J Friedman, Jeff Gelles, et al.Biorxiv : the Preprint Server for Biology|January 30, 2023
Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closingAudra Amasino, Shalini Gupta, Larry J Friedman, et al.Proceedings of the National Academy of Sciences of the United States of America|July 10, 2023
Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closingAudra L Amasino, Shalini Gupta, Larry J Friedman, et al.Biorxiv : the Preprint Server for Biology|July 3, 2023
Changing protein-DNA interactions promote ORC binding site exchange during replication origin licensingAnnie Zhang, Larry J Friedman, Jeff Gelles, et al.Biorxiv : the Preprint Server for Biology|June 4, 2025
An Orc6 tether mediates ORC binding site switching during replication origin licensingDavid Driscoll, Larry J Friedman, Jeff Gelles, et al.Proceedings of the National Academy of Sciences of the United States of America|July 18, 2023
Changing protein-DNA interactions promote ORC binding-site exchange during replication origin licensingAnnie Zhang, Larry J Friedman, Jeff Gelles, et al.Proceedings of the National Academy of Sciences of the United States of America|October 7, 2025
An Orc6 tether mediates ORC binding-site switching during replication origin licensingDavid Driscoll, Larry J Friedman, Jeff Gelles, et al.Elife|August 7, 2019
A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwindingKanokwan Champasa, Caitlin Blank, Larry J Friedman, et al.Cell|April 21, 2015
Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loadingSimina Ticau, Larry J Friedman, Nikola A Ivica, et al.Methods (San Diego, Calif.)|June 3, 2015
Multi-wavelength single-molecule fluorescence analysis of transcription mechanismsLarry J Friedman, Jeff GellesPageof 45