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Clinical Pharmacology and Therapeutics|December 8, 2022
Therapeutic Protein Drug Interactions: A White Paper From the International Consortium for Innovation and Quality in Pharmaceutical DevelopmentDavid E Coutant, David W Boulton, Upendra P Dahal, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 3, 2020
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk AssessmentSimon G Wong, Diane Ramsden, Shannon Dallas, et al.The International Journal of Neuropsychopharmacology|July 10, 2008
Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neuronsXuefei Wu, Po See Chen, Shannon Dallas, et al.Biomaterials|December 23, 2011
Tethered spheroids as an in vitro hepatocyte model for drug safety screeningLei Xia, Rashidah Binte Sakban, Yinghua Qu, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 1, 2018
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical RelevanceJane R Kenny, Diane Ramsden, David B Buckley, et al.Biomaterials|July 12, 2011
Galactosylated cellulosic sponge for multi-well drug safety testingBramasta Nugraha, Xin Hong, Xuejun Mo, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 25, 2017
Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive ControlNiresh Hariparsad, Diane Ramsden, Jairam Palamanda, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 24, 2014
Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statinsLaurent Salphati, Xiaoyan Chu, Liangfu Chen, et al.Molecular Pharmacology|February 20, 2016
Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse ModelShannon Dallas, Laurent Salphati, David Gomez-Zepeda, et al.Journal of Medicinal Chemistry|July 19, 2021
Gut-Restricted Selective Cyclooxygenase-2 (COX-2) Inhibitors for Chemoprevention of Colorectal CancerZhuming Zhang, Avijit Ghosh, Peter J Connolly, et al.Pageof 4