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Journal of Medicinal Chemistry
|
June 8, 2023
Precise Conformational Control Yielding Highly Potent and Exceptionally Selective BRD4 Degraders with Strong Antitumor Activity
Jiantao Hu, Biao Hu, Fuming Xu, et al.
ACS Medicinal Chemistry Letters
|
July 3, 2010
Structure-Based Design of Conformationally Constrained, Cell-Permeable STAT3 Inhibitors
Jianyong Chen, Longchuan Bai, Denzil Bernard, et al.
Journal of Medicinal Chemistry
|
December 16, 2014
Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles
Angelo Aguilar, Wei Sun, Liu Liu, et al.
Cancer Research
|
March 26, 2009
TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer: involvement of Notch-1 signaling pathway
Zhiwei Wang, Asfar Sohail Azmi, Aamir Ahmad, et al.
Leukemia
|
April 15, 2026
Activity of PROTAC MDM2 degrader in primary leukemia cells and PDX models
Malathi Kandarpa, Luke F Peterson, Harish Potu, et al.
Plos One
|
June 13, 2015
Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment
C Gianna Hoffman-Luca, Chao-Yie Yang, Jianfeng Lu, et al.
Molecular Cancer Therapeutics
|
July 23, 2008
Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair
Mahmoud Toulany, Rainer Kehlbach, Urszula Florczak, et al.
Molecular Pharmaceutics
|
September 18, 2010
Superparamagnetic iron oxide nanotheranostics for targeted cancer cell imaging and pH-dependent intracellular drug release
Peng Zou, Yanke Yu, Y Andrew Wang, et al.
ACS Medicinal Chemistry Letters
|
October 18, 2023
Discovery of Pyrrolo[2,3-<i>c</i>]pyridines as Potent and Reversible LSD1 Inhibitors
Canhui Zheng, Rohan Kalyan Rej, Mi Wang, et al.
Journal of Medicinal Chemistry
|
June 23, 2006
Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy
Yipin Lu, Zaneta Nikolovska-Coleska, Xueliang Fang, et al.
Page
of 48
Search research articles
Search
Showing results (151-160 of 480) with videos related to
Sort By:
Page
of 48
Journal of Medicinal Chemistry
|
June 8, 2023
Precise Conformational Control Yielding Highly Potent and Exceptionally Selective BRD4 Degraders with Strong Antitumor Activity
Jiantao Hu, Biao Hu, Fuming Xu, et al.
ACS Medicinal Chemistry Letters
|
July 3, 2010
Structure-Based Design of Conformationally Constrained, Cell-Permeable STAT3 Inhibitors
Jianyong Chen, Longchuan Bai, Denzil Bernard, et al.
Journal of Medicinal Chemistry
|
December 16, 2014
Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles
Angelo Aguilar, Wei Sun, Liu Liu, et al.
Cancer Research
|
March 26, 2009
TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer: involvement of Notch-1 signaling pathway
Zhiwei Wang, Asfar Sohail Azmi, Aamir Ahmad, et al.
Leukemia
|
April 15, 2026
Activity of PROTAC MDM2 degrader in primary leukemia cells and PDX models
Malathi Kandarpa, Luke F Peterson, Harish Potu, et al.
Plos One
|
June 13, 2015
Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment
C Gianna Hoffman-Luca, Chao-Yie Yang, Jianfeng Lu, et al.
Molecular Cancer Therapeutics
|
July 23, 2008
Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair
Mahmoud Toulany, Rainer Kehlbach, Urszula Florczak, et al.
Molecular Pharmaceutics
|
September 18, 2010
Superparamagnetic iron oxide nanotheranostics for targeted cancer cell imaging and pH-dependent intracellular drug release
Peng Zou, Yanke Yu, Y Andrew Wang, et al.
ACS Medicinal Chemistry Letters
|
October 18, 2023
Discovery of Pyrrolo[2,3-<i>c</i>]pyridines as Potent and Reversible LSD1 Inhibitors
Canhui Zheng, Rohan Kalyan Rej, Mi Wang, et al.
Journal of Medicinal Chemistry
|
June 23, 2006
Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy
Yipin Lu, Zaneta Nikolovska-Coleska, Xueliang Fang, et al.
Page
of 48