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Journal of Medicinal Chemistry
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July 13, 2023
Discovery of LNP1892: A Precision Calcimimetic for the Treatment of Secondary Hyperparathyroidism
Manojkumar R Shukla, Gayathri Sadasivam, Ankush Sarde, et al.
Regulatory Toxicology and Pharmacology : RTP
|
May 22, 2021
Regulatory safety pharmacology and toxicity assessments of a standardized stem extract of Cassia occidentalis Linn. in rodents
Madhav Nilakanth Mugale, Shubha Shukla, Manish K Chourasia, et al.
European Journal of Pharmacology
|
May 31, 2022
Discovery and pre-clinical characterization of a selective PI3Kδ inhibitor, LL-00071210 in rheumatoid arthritis
Vijay Kanoje, Dilip Pandey, Akshaya Wagh, et al.
Science (New York, N.Y.)
|
August 22, 2020
An orally available non-nucleotide STING agonist with antitumor activity
Bo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, et al.
Journal of Medicinal Chemistry
|
November 23, 2019
Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization
Neelima Sinha, Navnath P Karche, Mahip Kalyan Verma, et al.
ACS Medicinal Chemistry Letters
|
July 14, 2026
Discovery of MK-2118, a Small-Molecule Agonist of STING
Timothy Henderson, Michael D Altman, Alexei V Buevich, et al.
Journal of Medicinal Chemistry
|
December 10, 2020
Discovery of a Potent and Selective PI3Kδ Inhibitor (<i>S</i>)-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4<i>H</i>-quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models
Manojkumar R Shukla, Sukanya Patra, Mahip Verma, et al.
Journal of Medicinal Chemistry
|
November 29, 2021
Discovery of a Novel Potent and Selective Calcium Release-Activated Calcium Channel Inhibitor: 2,6-Difluoro-<i>N</i>-(2'-methyl-3'-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-[1,1'-biphenyl]-4-yl)benzamide. Structure-Activity Relationship and Preclinical Characterization
Nilesh Raghunath Khedkar, Nageswara Rao Irlapatti, Disha Dadke, et al.
Journal of Medicinal Chemistry
|
May 6, 2020
Discovery of Potent, Selective, and State-Dependent Na<sub>V</sub>1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides
Vidya Ramdas, Rashmi Talwar, Vijay Kanoje, et al.
Bioorganic & Medicinal Chemistry
|
October 29, 2020
Discovery of isoquinolinone and naphthyridinone-based inhibitors of poly(ADP-ribose) polymerase-1 (PARP1) as anticancer agents: Structure activity relationship and preclinical characterization
Navnath P Karche, Mandar Bhonde, Neelima Sinha, et al.
Page
of 11
Search research articles
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Showing results (91-100 of 101) with videos related to
Sort By:
Page
of 11
Journal of Medicinal Chemistry
|
July 13, 2023
Discovery of LNP1892: A Precision Calcimimetic for the Treatment of Secondary Hyperparathyroidism
Manojkumar R Shukla, Gayathri Sadasivam, Ankush Sarde, et al.
Regulatory Toxicology and Pharmacology : RTP
|
May 22, 2021
Regulatory safety pharmacology and toxicity assessments of a standardized stem extract of Cassia occidentalis Linn. in rodents
Madhav Nilakanth Mugale, Shubha Shukla, Manish K Chourasia, et al.
European Journal of Pharmacology
|
May 31, 2022
Discovery and pre-clinical characterization of a selective PI3Kδ inhibitor, LL-00071210 in rheumatoid arthritis
Vijay Kanoje, Dilip Pandey, Akshaya Wagh, et al.
Science (New York, N.Y.)
|
August 22, 2020
An orally available non-nucleotide STING agonist with antitumor activity
Bo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, et al.
Journal of Medicinal Chemistry
|
November 23, 2019
Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization
Neelima Sinha, Navnath P Karche, Mahip Kalyan Verma, et al.
ACS Medicinal Chemistry Letters
|
July 14, 2026
Discovery of MK-2118, a Small-Molecule Agonist of STING
Timothy Henderson, Michael D Altman, Alexei V Buevich, et al.
Journal of Medicinal Chemistry
|
December 10, 2020
Discovery of a Potent and Selective PI3Kδ Inhibitor (<i>S</i>)-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4<i>H</i>-quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models
Manojkumar R Shukla, Sukanya Patra, Mahip Verma, et al.
Journal of Medicinal Chemistry
|
November 29, 2021
Discovery of a Novel Potent and Selective Calcium Release-Activated Calcium Channel Inhibitor: 2,6-Difluoro-<i>N</i>-(2'-methyl-3'-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-[1,1'-biphenyl]-4-yl)benzamide. Structure-Activity Relationship and Preclinical Characterization
Nilesh Raghunath Khedkar, Nageswara Rao Irlapatti, Disha Dadke, et al.
Journal of Medicinal Chemistry
|
May 6, 2020
Discovery of Potent, Selective, and State-Dependent Na<sub>V</sub>1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides
Vidya Ramdas, Rashmi Talwar, Vijay Kanoje, et al.
Bioorganic & Medicinal Chemistry
|
October 29, 2020
Discovery of isoquinolinone and naphthyridinone-based inhibitors of poly(ADP-ribose) polymerase-1 (PARP1) as anticancer agents: Structure activity relationship and preclinical characterization
Navnath P Karche, Mandar Bhonde, Neelima Sinha, et al.
Page
of 11