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Biomedicines|October 28, 2023
Apabetalone, a Clinical-Stage, Selective BET Inhibitor, Opposes DUX4 Target Gene Expression in Primary Human FSHD Muscle CellsChristopher D Sarsons, Dean Gilham, Laura M Tsujikawa, et al.Journal of the American Academy of Child and Adolescent Psychiatry|August 14, 2008
Attention bias toward threat in pediatric anxiety disordersAmy Krain Roy, Roma A Vasa, Maggie Bruck, et al.American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions|October 14, 2017
Selective BET Protein Inhibition with Apabetalone and Cardiovascular Events: A Pooled Analysis of Trials in Patients with Coronary Artery DiseaseStephen J Nicholls, Kausik K Ray, Jan O Johansson, et al.American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions|August 30, 2018
The Effect of Bromodomain and Extra-Terminal Inhibitor Apabetalone on Attenuated Coronary Atherosclerotic Plaque: Insights from the ASSURE TrialDaisuke Shishikura, Yu Kataoka, Satoshi Honda, et al.Kidney International Reports|June 2, 2018
Benefit of Apabetalone on Plasma Proteins in Renal DiseaseSylwia Wasiak, Laura M Tsujikawa, Christopher Halliday, et al.Biomedicines|June 28, 2023
Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal ImpairmentDean Gilham, Sylwia Wasiak, Brooke D Rakai, et al.International Immunopharmacology|March 1, 2023
Dual mechanism: Epigenetic inhibitor apabetalone reduces SARS-CoV-2 Delta and Omicron variant spike binding and attenuates SARS-CoV-2 RNA induced inflammationLi Fu, Dean Gilham, Stephanie C Stotz, et al.Biophysical Reviews|September 2, 2021
A tribute to Dr. Serge N. Timasheff, our mentorKirk Aune, James Lee, V Prakash, et al.Pharmacology Research & Perspectives|April 13, 2022
Inhibition of epigenetic reader proteins by apabetalone counters inflammation in activated innate immune cells from Fabry disease patients receiving enzyme replacement therapyLi Fu, Sylwia Wasiak, Laura M Tsujikawa, et al.JAMA|March 29, 2020
Effect of Apabetalone Added to Standard Therapy on Major Adverse Cardiovascular Events in Patients With Recent Acute Coronary Syndrome and Type 2 Diabetes: A Randomized Clinical TrialKausik K Ray, Stephen J Nicholls, Kevin A Buhr, et al.Pageof 13