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Bioorganic & Medicinal Chemistry|December 4, 2003
Synthesis and opioid activity of N,N-dimethyl-Dmt-Tic-NH-CH(R)-R' analogues: acquisition of potent delta antagonismGianfranco Balboni, Severo Salvadori, Remo Guerrini, et al.The Journal of Pharmacology and Experimental Therapeutics|January 14, 2004
Novel 2',6'-dimethyl-L-tyrosine-containing pyrazinone opioid mimetic mu-agonists with potent antinociceptive activity in miceYunden Jinsmaa, Yoshio Okada, Yuko Tsuda, et al.International Journal of Molecular Sciences|September 23, 2020
Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics SimulationsTihomir Tomašič, Martina Durcik, Bradley M Keegan, et al.Pharmaceuticals (Basel, Switzerland)|August 28, 2021
Selective DNA Gyrase Inhibitors: Multi-Target in Silico Profiling with 3D-PharmacophoresTihomir Tomašič, Asta Zubrienė, Žiga Skok, et al.Bioorganic & Medicinal Chemistry|September 14, 2007
A new opioid designed multiple ligand derived from the micro opioid agonist endomorphin-2 and the delta opioid antagonist pharmacophore Dmt-TicSevero Salvadori, Claudio Trapella, Stella Fiorini, et al.Bioorganic & Medicinal Chemistry Letters|September 5, 2006
Synthesis of 3,6-bis[H-Tyr/H-Dmt-NH(CH2)m,n]-2(1H)pyrazinone derivatives: function of alkyl chain length on opioid activityKimitaka Shiotani, Tingyou Li, Anna Miyazaki, et al.Journal of Medicinal Chemistry|December 3, 2002
Crystal structures of dipeptides containing the Dmt-Tic pharmacophoreSharon D Bryant, Clifford George, Judith L Flippen-Anderson, et al.Molecules (Basel, Switzerland)|December 16, 2020
Parameters for Irreversible Inactivation of Monoamine OxidaseRona R Ramsay, Livia Basile, Antonin Maniquet, et al.Journal of Medicinal Chemistry|August 19, 2005
From the potent and selective mu opioid receptor agonist H-Dmt-d-Arg-Phe-Lys-NH(2) to the potent delta antagonist H-Dmt-Tic-Phe-Lys(Z)-OHGianfranco Balboni, Maria Teresa Cocco, Severo Salvadori, et al.Chemical & Pharmaceutical Bulletin|September 6, 2005
Studies on the mechanism of 1,2-dihydropyrazin-2-one ring formation from dipeptidyl chloromethyl ketone and its chemical properties: immediate deamination during catalytic hydrogenationAnna Miyazaki, Yutaka Fujisawa, Kimitaka Shiotani, et al.Pageof 5