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Journal of Medicinal Chemistry|January 22, 2005
Development of potent mu-opioid receptor ligands using unique tyrosine analogues of endomorphin-2Tingyou Li, Yoshio Fujita, Yuko Tsuda, et al.Bioorganic & Medicinal Chemistry Letters|September 11, 2007
Design and synthesis of opioidmimetics containing 2',6'-dimethyl-L-tyrosine and a pyrazinone-ring platformKimitaka Shiotani, Tingyou Li, Anna Miyazaki, et al.Journal of Medicinal Chemistry|December 14, 2004
Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-TicGianfranco Balboni, Severo Salvadori, Alessandro Dal Piaz, et al.Journal of Medicinal Chemistry|May 15, 2007
Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligandsTingyou Li, Kimitaka Shiotani, Anna Miyazaki, et al.Journal of Medicinal Chemistry|September 1, 2006
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophoreGianfranco Balboni, Valentina Onnis, Cenzo Congiu, et al.European Journal of Pharmacology|February 17, 2005
Differentiation of opioid receptor preference by [Dmt1]endomorphin-2-mediated antinociception in the mouseYunden Jinsmaa, Yoshio Fujita, Kimitaka Shiotani, et al.Medicinal Chemistry (Shariqah (United Arab Emirates))|November 30, 2007
Synthesis of opioidmimetics, 3-[H-Dmt-NH(CH(2))(m)]-6-[H-Dmt-NH(CH(2))(n)]-2(1H)-pyrazinones, and studies on structure-activity relationshipsKimitaka Shiotani, Anna Miyazaki, Tingyou Li, et al.Bioorganic & Medicinal Chemistry|April 3, 2003
Structural studies of [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bondYoshio Okada, Yoshio Fujita, Takashi Motoyama, et al.Journal of Medicinal Chemistry|June 23, 2006
New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligandsSteven Ballet, Severo Salvadori, Claudio Trapella, et al.Journal of Medicinal Chemistry|July 11, 2003
Unique high-affinity synthetic mu-opioid receptor agonists with central- and systemic-mediated analgesiaYoshio Okada, Yuko Tsuda, Yoshio Fujita, et al.Pageof 5