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The Journal of Biological Chemistry|October 27, 2016
Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall ComponentCullen L Myers, Franco K K Li, Byoung-Mo Koo, et al.Cell Reports|July 23, 2020
Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds against Klebsiella pneumoniaeBrent S Weber, Aaron M De Jong, Amelia B Y Guo, et al.Nature Microbiology|January 3, 2025
Exploiting the fitness cost of metallo-β-lactamase expression can overcome antibiotic resistance in bacterial pathogensMegan M Tu, Lindsey A Carfrae, Kenneth Rachwalski, et al.Proceedings of the National Academy of Sciences of the United States of America|August 19, 2015
Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthaseMaya A Farha, Tomasz L Czarny, Cullen L Myers, et al.Nature Communications|January 16, 2019
A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella TyphimuriumMichael J Ellis, Caressa N Tsai, Jarrod W Johnson, et al.Nature Microbiology|March 7, 2017
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistanceJonathan M Stokes, Craig R MacNair, Bushra Ilyas, et al.Research Square|January 29, 2025
A microbial natural product fractionation library screen with HRMS/MS dereplication identifies new lipopeptaibiotics against Candida aurisGerard Wright, Xuefei Chen, Kalinka Koteva, et al.Nature Chemical Biology|February 2, 2016
Assembly and clustering of natural antibiotics guides target identificationChad W Johnston, Michael A Skinnider, Chris A Dejong, et al.Cell Reports|April 5, 2024
A platform for predicting mechanism of action based on bacterial transcriptional responses identifies an unusual DNA gyrase inhibitorShawn French, Amelia Bing Ya Guo, Michael J Ellis, et al.Nature Microbiology|May 1, 2023
Inhibiting fatty acid synthesis overcomes colistin resistanceLindsey A Carfrae, Kenneth Rachwalski, Shawn French, et al.Pageof 4