Showing results (1-10 of 12) with videos related to
Sort By:
Pageof 2
Organic Letters|December 17, 2008
Total synthesis of (+)-psymberin (irciniastatin A): catalytic reagent control as the strategic cornerstoneAmos B Smith, Jon A Jurica, Shawn P WalshOrganic Letters|December 31, 2004
Diversity-oriented synthesis of polyketide natural products via iterative chemo- and stereoselective functionalization of polyenoates: development of a unified approach for the C(1-19) segments of lituarines A-CAmos B Smith, Shawn P Walsh, Michael Frohn, et al.The Journal of Organic Chemistry|March 21, 2013
Total synthesis of (+)-irciniastatin A (a.k.a. psymberin) and (-)-irciniastatin BChihui An, Jon A Jurica, Shawn P Walsh, et al.Bioorganic & Medicinal Chemistry Letters|April 26, 2011
3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonistsShawn P Walsh, Alexandra Severino, Changyou Zhou, et al.Journal of Medicinal Chemistry|January 24, 2003
Furoyl and benzofuroyl pyrroloquinolones as potent and selective PDE5 inhibitors for treatment of erectile dysfunctionWeiqin Jiang, Zhihua Sui, Mark J Macielag, et al.Hypertension (Dallas, Tex. : 1979)|December 7, 2016
Chronic Inhibition of Renal Outer Medullary Potassium Channel Not Only Prevented but Also Reversed Development of Hypertension and End-Organ Damage in Dahl Salt-Sensitive RatsXiaoyan Zhou, Michael J Forrest, Wanda Sharif-Rodriguez, et al.Bioorganic & Medicinal Chemistry Letters|October 1, 2013
Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-oneHaifeng Tang, Reynald K de Jesus, Shawn P Walsh, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism DiureticsHaifeng Tang, Shawn P Walsh, Yan Yan, et al.Bioorganic & Medicinal Chemistry Letters|March 28, 2016
Differentiation of ROMK potency from hERG potency in the phenacetyl piperazine series through heterocycle incorporationShawn P Walsh, Aurash Shahripour, Haifeng Tang, et al.ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart FailureHaifeng Tang, Yuping Zhu, Nardos Teumelsan, et al.Pageof 2