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Current Opinion in Systems Biology|May 16, 2019
Extracting Complementary Insights from Molecular Phenotypes for Prioritization of Disease-Associated MutationsShayne D Wierbowski, Robert Fragoza, Siqi Liang, et al.Protein Science : a Publication of the Protein Society|November 14, 2019
Cross-docking benchmark for automated pose and ranking prediction of ligand bindingShayne D Wierbowski, Bentley M Wingert, Jim Zheng, et al.Digital Discovery|February 27, 2026
Precision fragment addition: domain-specific DeepFrag2 models for smarter lead optimizationCésar R García-Jacas, Harrison Green, Shayne D Wierbowski, et al.Nature Methods|September 30, 2020
Structure-based validation can drastically underestimate error rate in proteome-wide cross-linking mass spectrometry studiesKumar Yugandhar, Ting-Yi Wang, Shayne D Wierbowski, et al.Genome Research|December 29, 2021
A full-proteome, interaction-specific characterization of mutational hotspots across human cancersSiwei Chen, Yuan Liu, Yingying Zhang, et al.Nature Genetics|September 22, 2020
Transcription imparts architecture, function and logic to enhancer unitsNathaniel D Tippens, Jin Liang, Alden King-Yung Leung, et al.Nature Methods|November 30, 2021
A 3D structural SARS-CoV-2-human interactome to explore genetic and drug perturbationsShayne D Wierbowski, Siqi Liang, Yuan Liu, et al.Nature Communications|January 24, 2025
A multiscale functional map of somatic mutations in cancer integrating protein structure and network topologyYingying Zhang, Alden K Leung, Jin Joo Kang, et al.Nature Communications|September 14, 2019
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populationsRobert Fragoza, Jishnu Das, Shayne D Wierbowski, et al.Proceedings of the National Academy of Sciences of the United States of America|May 14, 2020
A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for riceShayne D Wierbowski, Tommy V Vo, Pascal Falter-Braun, et al.Pageof 2