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Bioorganic & Medicinal Chemistry Letters|September 16, 2008
Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modelingYunsong Tong, Kent D Stewart, Sheela Thomas, et al.Pediatric Research|March 5, 2024
Temperature probe placement in very preterm infants during delivery room stabilization: an open-label randomized trialPranav R Jani, Rajesh Maheshwari, Hannah Skelton, et al.Bioorganic & Medicinal Chemistry Letters|July 1, 2008
Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituentGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.Journal of Medicinal Chemistry|January 20, 2006
Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesisAndrew M Petros, Jurgen Dinges, David J Augeri, et al.Journal of Medicinal Chemistry|November 6, 2009
Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agentsYunsong Tong, Jennifer J Bouska, Paul A Ellis, et al.Bioorganic & Medicinal Chemistry Letters|April 11, 2006
Isoquinoline-pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activityGui-Dong Zhu, Jianchun Gong, Akiyo Claiborne, et al.Bioorganic & Medicinal Chemistry Letters|January 18, 2006
Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancerQun Li, Keith W Woods, Sheela Thomas, et al.Journal of Medicinal Chemistry|March 27, 2010
Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitorThomas D Penning, Gui-Dong Zhu, Jianchun Gong, et al.Bioorganic & Medicinal Chemistry|June 11, 2008
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.Journal of Medicinal Chemistry|May 26, 2007
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotensionGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.Pageof 2