Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Shehab Ismail

Showing results (21-30 of 39) with videos related to

Pageof 4
Sort By:
Journal of Medicinal Chemistry|June 3, 2014
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding siteGunther Zimmermann, Carsten Schultz-Fademrecht, Philipp Küchler, et al.
Chembiochem : a European Journal of Chemical Biology|November 18, 2025
Development of a Genetically Encoded and Potent PDE6D InhibitorAtanasio Gómez-Mulas, Elisabeth Schaffner-Reckinger, Hanne Peeters, et al.
Chembiochem : a European Journal of Chemical Biology|July 22, 2014
Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivativesKenny Bravo-Rodriguez, Ahmed F Ismail-Ali, Stephan Klopries, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|November 4, 2016
Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding SiteSandip Murarka, Pablo Martín-Gago, Carsten Schultz-Fademrecht, et al.
Nature|May 24, 2013
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signallingGunther Zimmermann, Björn Papke, Shehab Ismail, et al.
Biochemistry|February 12, 2026
KRAS Can Bind to FTase Despite Disruption of the CAAX Binding SiteMartin Carion, Rebeca Cuesta, Dominika Kowalczyk, et al.
The Journal of Cell Biology|October 8, 2021
PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasivenessNicolas Rabas, Sarah Palmer, Louise Mitchell, et al.
Angewandte Chemie (International Ed. in English)|January 21, 2017
A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2Pablo Martín-Gago, Eyad K Fansa, Christian H Klein, et al.
Life Science Alliance|January 15, 2025
UNC119 regulates T-cell receptor signalling in primary T cells and T acute lymphocytic leukaemiaYouhani Samarakoon, Tamas Yelland, Esther Garcia-Gonzalez, et al.
Science Signaling|February 7, 2019
Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signalingFernanda G Kugeratski, Samuel J Atkinson, Lisa J Neilson, et al.
Pageof 4

Showing results (21-30 of 39) with videos related to

Sort By:
Pageof 4
Journal of Medicinal Chemistry|June 3, 2014
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding siteGunther Zimmermann, Carsten Schultz-Fademrecht, Philipp Küchler, et al.
Chembiochem : a European Journal of Chemical Biology|November 18, 2025
Development of a Genetically Encoded and Potent PDE6D InhibitorAtanasio Gómez-Mulas, Elisabeth Schaffner-Reckinger, Hanne Peeters, et al.
Chembiochem : a European Journal of Chemical Biology|July 22, 2014
Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivativesKenny Bravo-Rodriguez, Ahmed F Ismail-Ali, Stephan Klopries, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|November 4, 2016
Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding SiteSandip Murarka, Pablo Martín-Gago, Carsten Schultz-Fademrecht, et al.
Nature|May 24, 2013
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signallingGunther Zimmermann, Björn Papke, Shehab Ismail, et al.
Biochemistry|February 12, 2026
KRAS Can Bind to FTase Despite Disruption of the CAAX Binding SiteMartin Carion, Rebeca Cuesta, Dominika Kowalczyk, et al.
The Journal of Cell Biology|October 8, 2021
PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasivenessNicolas Rabas, Sarah Palmer, Louise Mitchell, et al.
Angewandte Chemie (International Ed. in English)|January 21, 2017
A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2Pablo Martín-Gago, Eyad K Fansa, Christian H Klein, et al.
Life Science Alliance|January 15, 2025
UNC119 regulates T-cell receptor signalling in primary T cells and T acute lymphocytic leukaemiaYouhani Samarakoon, Tamas Yelland, Esther Garcia-Gonzalez, et al.
Science Signaling|February 7, 2019
Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signalingFernanda G Kugeratski, Samuel J Atkinson, Lisa J Neilson, et al.
Pageof 4