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Shelli R McAlpine

Showing results (21-30 of 65) with videos related to

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Chemistry (Weinheim an Der Bergstrasse, Germany)|September 3, 2020
Cyclic Peptides as Drugs for Intracellular Targets: The Next Frontier in Peptide Therapeutic DevelopmentLaura K Buckton, Marwa N Rahimi, Shelli R McAlpine
Bioorganic & Medicinal Chemistry Letters|December 24, 2013
A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock responseJeanette R McConnell, Leslie A Alexander, Shelli R McAlpine
RSC Medicinal Chemistry|April 26, 2021
Using NMR to identify binding regions for N and C-terminal Hsp90 inhibitors using Hsp90 domainsJeanette R McConnell, H Jane Dyson, Shelli R McAlpine
Bioorganic & Medicinal Chemistry Letters|August 11, 2007
Identification of Sansalvamide a analog potent against pancreatic cancer cell linesPo-Shen Pan, Kathleen L McGuire, Shelli R McAlpine
Bioorganic & Medicinal Chemistry Letters|December 16, 2014
The fungal natural product (1S,3S)-austrocortirubin induces DNA damage in HCT116 cells via a mechanism unique from other DNA damaging agentsYao Wang, Md Amirul Islam, Rohan A Davis, et al.
ACS Chemical Biology|September 29, 2011
Macrocycles that inhibit the binding between heat shock protein 90 and TPR-containing proteinsVeronica C Ardi, Leslie D Alexander, Victoria A Johnson, et al.
Current Opinion in Drug Discovery & Development|July 5, 2008
Conformationally based design of macrocycles as antitumor agentsErinprit K Singh, Robert P Sellers, Leslie D Alexander, et al.
Bioorganic & Medicinal Chemistry Letters|October 22, 2011
A small molecule that preferentially binds the closed conformation of Hsp90Leslie D Alexander, James R Partridge, David A Agard, et al.
Journal of Medicinal Chemistry|January 12, 2008
Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell linesKaterina Otrubova, Gerald Lushington, David Vander Velde, et al.
Chemical Communications (Cambridge, England)|March 29, 2019
Polymer mediated transport of the Hsp90 inhibitor LB76, a polar cyclic peptide, produces an Hsp90 cellular phenotypeMarwa N Rahimi, Henry G Foster, Shegufta N Farazi, et al.
Pageof 7

Showing results (21-30 of 65) with videos related to

Sort By:
Pageof 7
Chemistry (Weinheim an Der Bergstrasse, Germany)|September 3, 2020
Cyclic Peptides as Drugs for Intracellular Targets: The Next Frontier in Peptide Therapeutic DevelopmentLaura K Buckton, Marwa N Rahimi, Shelli R McAlpine
Bioorganic & Medicinal Chemistry Letters|December 24, 2013
A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock responseJeanette R McConnell, Leslie A Alexander, Shelli R McAlpine
RSC Medicinal Chemistry|April 26, 2021
Using NMR to identify binding regions for N and C-terminal Hsp90 inhibitors using Hsp90 domainsJeanette R McConnell, H Jane Dyson, Shelli R McAlpine
Bioorganic & Medicinal Chemistry Letters|August 11, 2007
Identification of Sansalvamide a analog potent against pancreatic cancer cell linesPo-Shen Pan, Kathleen L McGuire, Shelli R McAlpine
Bioorganic & Medicinal Chemistry Letters|December 16, 2014
The fungal natural product (1S,3S)-austrocortirubin induces DNA damage in HCT116 cells via a mechanism unique from other DNA damaging agentsYao Wang, Md Amirul Islam, Rohan A Davis, et al.
ACS Chemical Biology|September 29, 2011
Macrocycles that inhibit the binding between heat shock protein 90 and TPR-containing proteinsVeronica C Ardi, Leslie D Alexander, Victoria A Johnson, et al.
Current Opinion in Drug Discovery & Development|July 5, 2008
Conformationally based design of macrocycles as antitumor agentsErinprit K Singh, Robert P Sellers, Leslie D Alexander, et al.
Bioorganic & Medicinal Chemistry Letters|October 22, 2011
A small molecule that preferentially binds the closed conformation of Hsp90Leslie D Alexander, James R Partridge, David A Agard, et al.
Journal of Medicinal Chemistry|January 12, 2008
Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell linesKaterina Otrubova, Gerald Lushington, David Vander Velde, et al.
Chemical Communications (Cambridge, England)|March 29, 2019
Polymer mediated transport of the Hsp90 inhibitor LB76, a polar cyclic peptide, produces an Hsp90 cellular phenotypeMarwa N Rahimi, Henry G Foster, Shegufta N Farazi, et al.
Pageof 7