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Journal of Medicinal Chemistry|October 7, 2017
Identification of a Novel 1,2,3,4-Tetrahydrobenzo[b][1,6]naphthyridine Analogue as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the Treatment of Alzheimer's DiseaseJole Fiorito, Jeremie Vendome, Faisal Saeed, et al.Bioorganic & Medicinal Chemistry Letters|July 15, 2023
Optimizing metabolic stability of phosphodiesterase 5 inhibitors: Discovery of a potent N-(pyridin-3-ylmethyl)quinoline derivative targeting synaptic plasticityElisa Zuccarello, Hong Zhang, Erica Acquarone, et al.Proceedings of the National Academy of Sciences of the United States of America|August 2, 2008
Locations of the beta1 transmembrane helices in the BK potassium channelGuoxia Liu, Sergey I Zakharov, Lin Yang, et al.Journal of Computational Chemistry|May 10, 2005
First-principle studies of intermolecular and intramolecular catalysis of protonated cocaineChang-Guo Zhan, Shi-Xian Deng, Jaime G Skiba, et al.Journal of Computer-Aided Molecular Design|September 10, 2011
Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotypeDušica Vidović, Yuli Xie, Alison Rinderspacher, et al.Iscience|December 23, 2020
<i>N</i>-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κBMatko Kalac, Michael Mangone, Alison Rinderspacher, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|June 26, 2009
Phosphodiesterase 5 inhibition improves synaptic function, memory, and amyloid-beta load in an Alzheimer's disease mouse modelDaniela Puzzo, Agnieszka Staniszewski, Shi Xian Deng, et al.Prostaglandins & Other Lipid Mediators|March 24, 2018
Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stabilityStevan Pecic, Amir A Zeki, Xiaoming Xu, et al.Biological Psychiatry|October 10, 2024
Prophylactic (R,S)-Ketamine and (2S,6S)-Hydroxynorketamine Decrease Fear Expression by Differentially Modulating Fear Neural EnsemblesAlessia Mastrodonato, Michelle Jin, Noelle Kee, et al.Science (New York, N.Y.)|April 10, 2004
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2Xander H T Wehrens, Stephan E Lehnart, Steven R Reiken, et al.Pageof 4