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Bioorganic & Medicinal Chemistry|March 20, 2008
Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonistKazunari Sakagami, Akito Yasuhara, Shigeyuki Chaki, et al.
CNS Drug Reviews|April 15, 2006
ATC0175: an orally active melanin-concentrating hormone receptor 1 antagonist for the potential treatment of depression and anxietyShigeyuki Chaki, Jun-ichi Yamaguchi, Hisaharu Yamada, et al.
The International Journal of Neuropsychopharmacology|October 30, 2016
Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with KetamineChao Dong, Ji-Chun Zhang, Wei Yao, et al.
European Journal of Pharmacology|February 9, 2012
R278995/CRA0450, a corticotropin-releasing factor (CRF(1)) receptor antagonist modulates REM sleep measures in rats: Implication for therapeutic indicationAbdallah Ahnaou, Thomas Steckler, Annick Heylen, et al.
Behavioural Brain Research|October 11, 2014
Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in ratsKazuaki Kawaura, Hiroyuki Koike, Kohnosuke Kinoshita, et al.
Pharmacology, Biochemistry, and Behavior|December 13, 2005
MCL0042: a nonpeptidic MC4 receptor antagonist and serotonin reuptake inhibitor with anxiolytic- and antidepressant-like activityShigeyuki Chaki, Yuichi Oshida, Shin-Ichi Ogawa, et al.
British Journal of Clinical Pharmacology|May 1, 2020
Safety and pharmacokinetic profiles of MGS0274 besylate (TS-134), a novel metabotropic glutamate 2/3 receptor agonist prodrug, in healthy subjectsMai Watanabe, Brian Marcy, Kohnosuke Kinoshita, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|May 27, 2018
(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in miceJun-Ichi Yamaguchi, Hidetoh Toki, Youge Qu, et al.
Neurochemistry International|January 28, 2003
Increase in secretion of glial cell line-derived neurotrophic factor from glial cell lines by inhibitors of vacuolar ATPaseMariko Nishiguchi, Kimiko Tokugawa, Kyoko Yamamoto, et al.
Life Sciences|October 2, 2002
In vitro and in vivo pharmacological profile of 4-(4-fluorobenzylidene)-1-[2-[5-(4-fluorophenyl)-1H-pyrazol-4-yl] ethyl] piperidine (NRA0161)Yoshiko Suzuki, Takeo Funakoshi, Shigeyuki Chaki, et al.
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