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Human Molecular Genetics|January 9, 2013
A new locus for X-linked dominant Charcot-Marie-Tooth disease (CMTX6) is caused by mutations in the pyruvate dehydrogenase kinase isoenzyme 3 (PDK3) geneMarina L Kennerson, Eppie M Yiu, David T Chuang, et al.The Journal of Biological Chemistry|December 21, 2013
Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocketShih-Chia Tso, Xiangbing Qi, Wen-Jun Gui, et al.European Biophysics Journal : EBJ|April 17, 2021
A multi-laboratory benchmark study of isothermal titration calorimetry (ITC) using Ca<sup>2+</sup> and Mg<sup>2+</sup> binding to EDTAAdrian Velazquez-Campoy, Bárbara Claro, Olga Abian, et al.Proceedings of the National Academy of Sciences of the United States of America|May 30, 2013
Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinaseShih-Chia Tso, Xiangbing Qi, Wen-Jun Gui, et al.The Journal of Biological Chemistry|June 5, 2014
Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinaseShih-Chia Tso, Wen-Jun Gui, Cheng-Yang Wu, et al.Nature Cell Biology|April 21, 2025
Mitochondrial NADPH fuels mitochondrial fatty acid synthesis and lipoylation to power oxidative metabolismDohun Kim, Rushendhiran Kesavan, Kevin Ryu, et al.Cell Metabolism|May 22, 2018
The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate LyasePhillip J White, Robert W McGarrah, Paul A Grimsrud, et al.Nature|May 8, 2024
The intrinsic substrate specificity of the human tyrosine kinomeTomer M Yaron-Barir, Brian A Joughin, Emily M Huntsman, et al.Pageof 3