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Journal of Medicinal Chemistry
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August 18, 2021
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5<sup>H88Y</sup> Mutant Mice
Ying Yun, Chenlu Zhang, Shimeng Guo, et al.
Nature Structural & Molecular Biology
|
August 15, 2022
Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119
Peiyu Xu, Sijie Huang, Shimeng Guo, et al.
Cell Discovery
|
December 27, 2022
Structures of adenosine receptor A<sub>2B</sub>R bound to endogenous and synthetic agonists
Hongmin Cai, Youwei Xu, Shimeng Guo, et al.
Nucleic Acids Research
|
June 9, 2025
Deciphering meiotic chromatin organization by SYCP3
Shimeng Guo, Yiran Zhang, Caifeng Fei, et al.
Journal of Medicinal Chemistry
|
April 6, 2026
Rational Design of Dual-Target Molecules via a Fragment-Merging Strategy: TGR5 Agonism and SSTR5 Antagonism
Chuhua Song, Yu Wang, Xiaoyu Han, et al.
Journal of Medicinal Chemistry
|
September 29, 2020
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
Junyou Li, Mengqi Liu, Yazhou Li, et al.
International Journal of Biological Macromolecules
|
April 4, 2025
KLF12 transcriptional activation by a novel LncRNA A930015D03Rik enhances melanoma metastasis
Meng Xiang, Ziyi Li, Jie Su, et al.
Nucleic Acids Research
|
January 21, 2026
Distal enhancers regulate mammalian early embryonic lineage differentiation through long-range interactions
Qianshu Zhu, Shimeng Guo, Juan Xie, et al.
Cell Discovery
|
January 9, 2025
Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR
Ping Luo, Wenwen Xin, Shimeng Guo, et al.
Cell Discovery
|
June 24, 2025
Molecular mechanism of pH sensing and activation in GPR4 reveals proton-mediated GPCR signaling
Chongzhao You, Shimeng Guo, Tianwei Zhang, et al.
Page
of 6
Search research articles
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Showing results (41-50 of 58) with videos related to
Sort By:
Page
of 6
Journal of Medicinal Chemistry
|
August 18, 2021
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5<sup>H88Y</sup> Mutant Mice
Ying Yun, Chenlu Zhang, Shimeng Guo, et al.
Nature Structural & Molecular Biology
|
August 15, 2022
Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119
Peiyu Xu, Sijie Huang, Shimeng Guo, et al.
Cell Discovery
|
December 27, 2022
Structures of adenosine receptor A<sub>2B</sub>R bound to endogenous and synthetic agonists
Hongmin Cai, Youwei Xu, Shimeng Guo, et al.
Nucleic Acids Research
|
June 9, 2025
Deciphering meiotic chromatin organization by SYCP3
Shimeng Guo, Yiran Zhang, Caifeng Fei, et al.
Journal of Medicinal Chemistry
|
April 6, 2026
Rational Design of Dual-Target Molecules via a Fragment-Merging Strategy: TGR5 Agonism and SSTR5 Antagonism
Chuhua Song, Yu Wang, Xiaoyu Han, et al.
Journal of Medicinal Chemistry
|
September 29, 2020
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
Junyou Li, Mengqi Liu, Yazhou Li, et al.
International Journal of Biological Macromolecules
|
April 4, 2025
KLF12 transcriptional activation by a novel LncRNA A930015D03Rik enhances melanoma metastasis
Meng Xiang, Ziyi Li, Jie Su, et al.
Nucleic Acids Research
|
January 21, 2026
Distal enhancers regulate mammalian early embryonic lineage differentiation through long-range interactions
Qianshu Zhu, Shimeng Guo, Juan Xie, et al.
Cell Discovery
|
January 9, 2025
Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR
Ping Luo, Wenwen Xin, Shimeng Guo, et al.
Cell Discovery
|
June 24, 2025
Molecular mechanism of pH sensing and activation in GPR4 reveals proton-mediated GPCR signaling
Chongzhao You, Shimeng Guo, Tianwei Zhang, et al.
Page
of 6