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Journal of Medicinal Chemistry|March 8, 2023
Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer AgentsYosuke Nishigaya, Shohei Takase, Tatsunobu Sumiya, et al.Bioorganic & Medicinal Chemistry Letters|June 24, 2024
Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatmentYosuke Nishigaya, Shohei Takase, Tatsunobu Sumiya, et al.Japanese Heart Journal|September 14, 2002
Angioscopic evaluation of stabilizing effects of an antilipemic agent, bezafibrate, on coronary plaques in patients with coronary artery disease: a multicenter prospective studyHidefumi Ohsawa, Yasumi Uchida, Yoshiharu Fujimori, et al.European Journal of Medicinal Chemistry|May 14, 2025
Discovery of potent substrate-type lysine methyltransferase G9a inhibitors for the treatment of sickle cell diseaseYosuke Nishigaya, Shohei Takase, Tatsunobu Sumiya, et al.Journal of Medicinal Chemistry|March 24, 2020
Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon CancerFumiyuki Shirai, Anna Mizutani, Yoko Yashiroda, et al.Nature Communications|January 12, 2023
A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expressionShohei Takase, Takashi Hiroyama, Fumiyuki Shirai, et al.Journal of Medicinal Chemistry|March 19, 2019
Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase InhibitorsFumiyuki Shirai, Takeshi Tsumura, Yoko Yashiroda, et al.Pageof 10