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Journal of Pharmaceutical Sciences|December 29, 2021
Assessment of Drug-drug Interaction and Optimization in Capecitabine and Irinotecan Combination Regimen using a Physiologically Based Pharmacokinetic ModelShuhei Sakai, Shinji Kobuchi, Yukako Ito, et al.Biopharmaceutics & Drug Disposition|December 29, 2018
Association between the pharmacokinetics of capecitabine and the plasma dihydrouracil to uracil ratio in rat: A surrogate biomarker for dihydropyrimidine dehydrogenase activityShinji Kobuchi, Mako Akutagawa, Yukako Ito, et al.Annals of Palliative Medicine|July 22, 2020
Effect of intact oxaliplatin in plasma on a cold allodynia after multiple administrations in colorectal cancer model ratsYukako Ito, Shinji Kobuchi, Mako Takeda, et al.Cancer Chemotherapy and Pharmacology|November 23, 2017
Pharmacokinetic and toxicodynamic evaluation of oxaliplatin-induced neuropathy and hematological toxicity in ratsYukako Ito, Shinji Kobuchi, Risa Shimizu, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|November 28, 2017
Circadian variations in the pharmacokinetics of capecitabine and its metabolites in ratsShinji Kobuchi, Yukiko Yazaki, Yukako Ito, et al.Biological & Pharmaceutical Bulletin|October 13, 2025
Association of Plasma Creatinine with Systemic Exposure to S-1 and Oxaliplatin in Two Types of Chronic Kidney Disease Animal ModelsTakumi Tanaka, Aika Tanaka, Shinji Kobuchi, et al.European Journal of Drug Metabolism and Pharmacokinetics|December 1, 2012
Pharmacokinetics of 5-fluorouracil and increased hepatic dihydropyrimidine dehydrogenase activity levels in 1,2-dimethylhydrazine-induced colorectal cancer model ratsShinji Kobuchi, Yukako Ito, Kae Okada, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|June 16, 2016
Development and validation of an LC-MS/MS method for the determination of tofogliflozin in plasma and its application to a pharmacokinetic study in ratsShinji Kobuchi, Megumi Matsuno, Etsuko Fukuda, et al.International Journal of Medical Sciences|April 15, 2016
Therapeutic Drug Monitoring of Vancomycin in Dermal Interstitial Fluid Using Dissolving MicroneedlesYukako Ito, Yuto Inagaki, Shinji Kobuchi, et al.Free Radical Research|April 11, 2012
Pharmacokinetics and distribution of fluvoxamine to the brain in rats under oxidative stressShinji Kobuchi, Keizo Fukushima, Yukako Ito, et al.Pageof 7