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Human Molecular Genetics|April 5, 2014
Distinct pathways leading to TDP-43-induced cellular dysfunctionsMakiko Yamashita, Takashi Nonaka, Shinobu Hirai, et al.
Journal of Neuroinflammation|October 12, 2024
Minocycline prevents early age-related cognitive decline in a mouse model of intellectual disability caused by ZBTB18/RP58 haploinsufficiencyTomoko Tanaka, Shinobu Hirai, Hiroyuki Manabe, et al.
The Journal of Biological Chemistry|January 16, 2016
Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43Takashi Nonaka, Genjiro Suzuki, Yoshinori Tanaka, et al.
Epilepsia|March 11, 2025
Optogenetically-induced sustained hypothalamic hyperexcitability impairs memory via thalamic spreadMasaki Sonoda, Hisao Aimi, Keisuke Kawasaki, et al.
Cell Reports|February 12, 2013
RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortexChiaki Ohtaka-Maruyama, Shinobu Hirai, Akiko Miwa, et al.
Journal of Psychiatric Research|May 19, 2023
Disease specific brain capillary angiopathy in schizophrenia, bipolar disorder, and Alzheimer's diseaseShinobu Hirai, Atsuhiro Sakuma, Yasuto Kunii, et al.
Developmental Biology|May 5, 2009
The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortexHaruo Okado, Chiaki Ohtaka-Maruyama, Yoshinobu Sugitani, et al.
Molecular Therapy. Nucleic Acids|April 10, 2025
Correcting tau isoform ratios with a long-acting antisense oligonucleotide alleviates 4R-tauopathy phenotypesKuniyuki Iwata-Endo, Kentaro Sahashi, Kaori Kawai, et al.
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