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Journal of Medicinal Chemistry|April 12, 2024
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main ProteaseYugendar R Alugubelli, Jing Xiao, Kaustav Khatua, et al.Biorxiv : the Preprint Server for Biology|January 4, 2022
The P3 O - Tert -Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease InhibitorsYuying Ma, Kai S Yang, Zhi Zachary Geng, et al.Biorxiv : the Preprint Server for Biology|January 4, 2022
The N -Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease InhibitorsYugendar R Alugubelli, Zhi Zachary Geng, Kai S Yang, et al.Cell Research|September 6, 2014
Systematically labeling developmental stage-specific genes for the study of pancreatic β-cell differentiation from human embryonic stem cellsHaisong Liu, Huan Yang, Dicong Zhu, et al.Science Advances|April 8, 2026
From vibrations to function: Spectroscopic detection and quantification of π-π stacking in drug-responsive protein complexesNarangerel Altangerel, Esther J Ocola, Benjamin W Neuman, et al.ACS Central Science|March 1, 2022
Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based AssayWenyue Cao, Chia-Chuan Dean Cho, Zhi Zachary Geng, et al.European Journal of Medicinal Chemistry|July 2, 2022
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antiviralsYuying Ma, Kai S Yang, Zhi Zachary Geng, et al.European Journal of Medicinal Chemistry|July 15, 2022
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antiviralsYugendar R Alugubelli, Zhi Zachary Geng, Kai S Yang, et al.Journal of the American Chemical Society|April 14, 2026
Nicotine-Inspired, De Novo-Designed SARS-CoV-2 Main Protease Inhibitors Reveal Unique Chemistry for Covalently Conjugating Both Cysteine and Histidine Residues in the Catalytic DyadSandeep Atla, Veerabhadra Vulupala, Yugendar R Alugubelli, et al.Journal of Medicinal Chemistry|August 10, 2023
A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main ProteaseZhi Zachary Geng, Sandeep Atla, Namir Shaabani, et al.Pageof 27