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Frontiers in Microbiology|December 20, 2018
Novel Acetamide Indirectly Targets Mycobacterial Transporter MmpL3 by Proton Motive Force DisruptionAnnanya Shetty, Zhujun Xu, Umayal Lakshmanan, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 21, 2026
A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycinCristina Colomer-Winter, Zeus J Nair, Jerome Y J Chua, et al.
The Journal of Biological Chemistry|September 29, 2019
A piperidinol-containing molecule is active against Mycobacterium tuberculosis by inhibiting the mycolic acid flippase activity of MmpL3Christian Dupont, Yushu Chen, Zhujun Xu, et al.
ACS Infectious Diseases|May 16, 2020
Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 InhibitionMing Li, Zheng Yen Phua, Yu Xi, et al.
Scientific Reports|August 19, 2017
MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasisGeorgia L Isom, Nathaniel J Davies, Zhi-Soon Chong, et al.
Mbio|January 11, 2023
Depleting Cationic Lipids Involved in Antimicrobial Resistance Drives Adaptive Lipid Remodeling in Enterococcus faecalisRafi Rashid, Zeus Jaren Nair, Dominic Ming Hao Chia, et al.
Journal of Bacteriology|October 27, 2020
Structure-Function Characterization of the Conserved Regulatory Mechanism of the Escherichia coli M48 Metalloprotease BepAJack A Bryant, Ian T Cadby, Zhi-Soon Chong, et al.
Bioorganic & Medicinal Chemistry|January 22, 2023
Auranofin inhibits virulence pathways in Pseudomonas aeruginosaJoey Kuok Hoong Yam, Leon Zhen Wei Tan, Ziyan Hong, et al.
Biorxiv : the Preprint Server for Biology|November 24, 2025
A bioluminescence-based chemical screen identifies a bactericidal naphthalene scaffold targeting MmpL3 in Mycobacterium abscessusSamsher Singh, Ria Sorayah, Yushu Chen, et al.
Cell Reports|April 24, 2026
A bioluminescence-based chemical screen identifies a bactericidal naphthalen-1-ylmethanamine scaffold targeting MmpL3 in Mycobacterium abscessusSamsher Singh, Ria Sorayah, Yushu Chen, et al.
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