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ACS Chemical Neuroscience|September 22, 2020
How Mutations Perturb γ-Secretase Active Site Studied by Free Energy SimulationsShu-Yu Chen, Martin Zacharias
Computational and Structural Biotechnology Journal|April 17, 2026
In Silico Analysis of Potential Stabilizer Binding Sites at Protein-RNA InterfacesLuis Vollmers, Shu-Yu Chen, Martin Zacharias
Journal of Medicinal Chemistry|December 7, 2023
How Modulator Binding at the Amyloidβ-γ-Secretase Interface Enhances Substrate Binding and Attenuates Membrane DistortionShu-Yu Chen, Matthias Koch, Lucía Chávez-Gutiérrez, et al.
Communications Biology|June 24, 2023
Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active siteShu-Yu Chen, Lukas P Feilen, Lucía Chávez-Gutiérrez, et al.
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