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Journal of Medicinal Chemistry|June 24, 2010
Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malariaBryan K S Yeung, Bin Zou, Matthias Rottmann, et al.Journal of Medicinal Chemistry|August 15, 2012
Solubility-driven optimization of phosphodiesterase-4 inhibitors leading to a clinical candidateNeil J Press, Roger J Taylor, Joseph D Fullerton, et al.ACS Medicinal Chemistry Letters|February 16, 2017
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1Julian R Levell, Thomas Caferro, Gregg Chenail, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of tetrahydropyrazolopyrimidine carboxamide derivatives as potent and orally active antitubercular agentsFumiaki Yokokawa, Gang Wang, Wai Ling Chan, et al.Nature Communications|October 13, 2015
FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26pStephen B Helliwell, Shantanu Karkare, Marc Bergdoll, et al.Journal of Medicinal Chemistry|May 24, 2021
Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary DiseaseDarren Le Grand, Martin Gosling, Urs Baettig, et al.Journal of Medicinal Chemistry|April 30, 2021
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive BacteriaGuillaume Lapointe, Colin K Skepper, Lauren M Holder, et al.Pageof 6